Yasukawa A, Takeda S, Takeda Y, Yasumoto A, Matsuoka N, Negayama K
Department of Urology, Kagawa Medical College.
Hinyokika Kiyo. 1987 Oct;33(10):1724-7.
Thirty-nine male patients with urethritis were studied for gonorrhoea or non-gonorrhoea infections. Only 2 patients were infected with N. gonorrhoeae, the other 37 patients were non-gonorrhoea urethritis (NGU). In 9 of these patients, C. trachomatis was identified and in 6 patients, U. urealyticum was isolated. No chlamydial urethritis was combined with ureaplasma. There was no clinical difference between chlamydia and ureaplasma infection, such as serous urethral discharge or mild pyuria. Minocycline was given orally at the dose of 200 mg daily for 7 to 42 days to these patients. Seven of the 9 patients (78%) with C. trachomatis and 7 of the 6 patients (67%) with U. urealyticum infection showed improvement of subjective and objective symptoms after minocycline. In no case, was an adverse reaction noted. Minocycline was effective in the treatment of both C. trachomatis and U. urealyticum urethral infection.
对39例尿道炎男性患者进行了淋病或非淋菌性感染研究。仅2例感染淋病奈瑟菌,其他37例为非淋菌性尿道炎(NGU)。其中9例患者检测出沙眼衣原体,6例患者分离出解脲脲原体。未发现衣原体尿道炎合并脲原体感染。衣原体感染和脲原体感染在临床症状上无差异,如浆液性尿道分泌物或轻度脓尿。给予这些患者口服米诺环素,剂量为每日200mg,疗程7至42天。9例沙眼衣原体感染患者中有7例(78%),6例解脲脲原体感染患者中有7例(67%)在服用米诺环素后主观和客观症状均有改善。未观察到不良反应。米诺环素对沙眼衣原体和解脲脲原体尿道感染均有效。