Kew M C, Hodkinson J
Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa.
Am J Gastroenterol. 1991 Aug;86(8):1083-5.
Spontaneous rupture of hepatocellular carcinoma occurs frequently in populations in which this tumor is common, but rarely in populations with a low incidence of the tumor. Rupture caused by blunt abdominal trauma has previously been reported in a single patient only. We describe three southern African black men who presented with an acute hemoperitoneum after blunt trauma to the abdomen, and in whom a moderate-size hepatocellular carcinoma was found at laparotomy to have ruptured. In two of the patients, it was possible to resect the tumor. This resectability rate is unusual in blacks with hepatocellular carcinoma, because the tumor is characteristically far advanced at the time of presentation and is rarely amenable to resection.
肝细胞癌自发性破裂在该肿瘤常见的人群中频繁发生,但在肿瘤发病率低的人群中则很少见。此前仅有1例患者报告过腹部钝性创伤导致的破裂。我们描述了3名南非黑人男性,他们在腹部遭受钝性创伤后出现急性血腹,剖腹探查时发现中等大小的肝细胞癌已破裂。其中2例患者可行肿瘤切除术。这种可切除率在患有肝细胞癌的黑人中并不常见,因为该肿瘤在出现时通常已处于晚期,很少适合切除。