Kishore R R
B-5/58 Safdarjung Enclave, New Delhi-110029, India.
Sci Eng Ethics. 2006 Jan;12(1):175-83. doi: 10.1007/s11948-006-0017-8.
Almost all ethical guidelines and legislative policies concerning biomedical research involving human subjects contain provisions about relevance of research for the participating populations, informed consent, adequate care for research induced injuries and several other safeguards but the poor continue to suffer. Globalization has further aggravated poor people's vulnerability by exposing them to international markets. Since the developing countries are abode of higher population of the poor they have become the unholy mines of this human ore for researchers. In this paper I examine various dimensions of poverty and analyze the international ethical responses in the area of biomedical research involving human subjects in order to determine their adequacy to protect the poor against exploitation and misuse and conclude that in view of the poor's inherent and extreme vulnerability and the failure of ethical pronouncements to protect them from misuse and exploitation, they should be excluded from being enrolled as research subjects.
几乎所有涉及人类受试者的生物医学研究的伦理准则和立法政策都包含有关研究对参与人群的相关性、知情同意、对研究所致伤害的充分护理以及其他一些保障措施的规定，但穷人仍在受苦。全球化通过使穷人接触国际市场，进一步加剧了他们的脆弱性。由于发展中国家是贫困人口较多的地方，它们已成为研究人员挖掘这种人类“矿石”的罪恶之地。在本文中，我审视了贫困的各个层面，并分析了在涉及人类受试者的生物医学研究领域的国际伦理回应，以确定它们在保护穷人免受剥削和滥用方面是否充分，并得出结论，鉴于穷人固有的极端脆弱性以及伦理声明未能保护他们免受滥用和剥削，应将他们排除在研究受试者之外。
