Kearney D, Donlon J B, Mendelson R M
Radiology Department, Royal Perth Hospital, Western Australia.
Australas Radiol. 1991 Feb;35(1):88-91. doi: 10.1111/j.1440-1673.1991.tb03003.x.
Fibrolamellar hepatocellular carcinoma is an uncommon histologic subtype of hepatocellular carcinoma, comprising 3.5% of all hepatocellular carcinomas in one large study (Brandt et al 1988). It usually occurs in young people, the average age being 18 years (Farhi et al 1983). It is not associated with cirrhosis and the serum alphafetoprotein is usually normal (Craig et al 1980). Fibrolamellar hepatocellular carcinoma has a more favourable prognosis than the usual hepatocellular carcinoma, with an average survival of 32 months from onset of symptoms, compared to 6 months for the usual type. The resectability rate and 5 year survival figures are also much better (Craig et al 1980). Hence distinguishing this histological subtype is important for surgical management and survival prognosis. This report describes a full radiological evaluation of such a case, covering the wide spectrum of relevant imaging modalities.
纤维板层型肝细胞癌是肝细胞癌中一种不常见的组织学亚型，在一项大型研究中占所有肝细胞癌的3.5%（布兰特等人，1988年）。它通常发生在年轻人中，平均年龄为18岁（法希等人，1983年）。它与肝硬化无关，血清甲胎蛋白通常正常（克雷格等人，1980年）。纤维板层型肝细胞癌的预后比普通肝细胞癌更有利，从症状出现起平均存活32个月，而普通类型为6个月。切除率和5年生存率也更好得多（克雷格等人，1980年）。因此，区分这种组织学亚型对于手术治疗和生存预后很重要。本报告描述了对这样一例病例的全面影像学评估，涵盖了广泛的相关成像方式。
