Liu Honghu, Longshore Doug, Williams John K, Rivkin Inna, Loeb Tamra, Warda Umme S, Carmona Jennifer, Wyatt Gail
UCLA Department of Medicine, Division of General Internal Medicine and Health Services Research, Los Angeles, California 90095-1736, USA.
AIDS Behav. 2006 May;10(3):279-86. doi: 10.1007/s10461-005-9041-y.
Substance abuse increases the risks for infections and impairs medication adherence among HIV/AIDS patients. However, little is known about the characteristics of substance abuse and its impact on medication adherence among HIV-positive women with a history of child sexual abuse (CSA). In the present study, 148 HIV-positive women with a history of CSA completed a structured interview assessing CSA severity, psychological status, substance abuse, medication adherence, and sexual decision-making. Severity of CSA was significantly associated with substance use but not with adherence. Participants who had used hard drugs and who had lower self-esteem and adherence self-efficacy reported significantly lower levels of adherence. Additional research on how CSA experiences impact health behaviors is needed to help develop culturally congruent interventions to reduce risk behaviors and facilitate better medication adherence for this vulnerable population.
药物滥用会增加感染风险，并损害艾滋病毒/艾滋病患者的药物治疗依从性。然而，对于有儿童性虐待（CSA）史的艾滋病毒阳性女性，药物滥用的特征及其对药物治疗依从性的影响却知之甚少。在本研究中，148名有CSA史的艾滋病毒阳性女性完成了一项结构化访谈，评估CSA的严重程度、心理状态、药物滥用、药物治疗依从性和性决策。CSA的严重程度与药物使用显著相关，但与依从性无关。使用过硬性毒品、自尊水平较低且依从自我效能较低的参与者报告的依从水平显著较低。需要进一步研究CSA经历如何影响健康行为，以帮助制定符合文化背景的干预措施，减少风险行为，并促进这一弱势群体更好地坚持药物治疗。
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