Rossi Carlotta, Simini Bruno, Brazzi Luca, Rossi Giancarlo, Radrizzani Danilo, Iapichino Gaetano, Bertolini Guido
Centro di Ricerche Cliniche per le Malattie Rare Aldo e Cele Daccò, Istituto di Ricerche Farmacologiche Mario Negri, Ranica, Italy.
Intensive Care Med. 2006 Apr;32(4):545-52. doi: 10.1007/s00134-006-0080-2. Epub 2006 Feb 25.
To analyze the costs of treating critically ill patients.
Multicenter, observational, prospective, cohort, bottom-up study on variable costs in 51 ICUs.
A total of 1,034 patients aged over 14 years who either spent less than 48 h in the ICU or had multiple trauma, major abdominal surgery, ischemic stroke, chronic obstructive pulmonary disease, cardiac failure, isolated head injury, acute lung injury/adult respiratory distress syndrome (ALI/ARDS), nontraumatic intracranial hemorrhage or coronary surgery.
Data recorded for each patient: length of ICU stay, and cost in euros of all diagnostic and therapeutic procedures, drugs and equipment used, and consultations by physicians from other units. To express cost-efficiency we calculated for each diagnostic group the cost per surviving patient (expenditure for all patients/number of surviving patients) and money loss per patient (expenditure for patients who died/total number of patients).
Median costs for a multiple trauma patient were euro 4076 and for coronary surgery patient euro 380. The variability is largely due to different lengths of ICU stay. Cost per surviving patient was higher for ALI/ARDS, nontraumatic intracranial hemorrhage, multiple trauma, and emergency abdominal surgery. Money loss per patient was higher for ALI/ARDS and lower for multiple trauma. Planned coronary and major abdominal surgery and short-stay patients were treated most cost-efficiently.
Cost of treatment in an ICU varies widely for different types of patients. Strategies are needed to contain the major determinants of high costs and low cost-efficiency.
分析危重症患者的治疗费用。
在51个重症监护病房(ICU)进行的多中心、观察性、前瞻性队列、自下而上的可变成本研究。
共1034例14岁以上患者,这些患者要么在ICU的停留时间少于48小时,要么患有多发伤、腹部大手术、缺血性中风、慢性阻塞性肺疾病、心力衰竭、单纯性颅脑损伤、急性肺损伤/成人呼吸窘迫综合征(ALI/ARDS)、非创伤性颅内出血或冠状动脉手术。
记录每位患者的数据:ICU住院时间,以及所有诊断和治疗程序、使用的药物和设备以及其他科室医生会诊的费用(以欧元计)。为了衡量成本效益,我们计算了每个诊断组中每位存活患者的成本(所有患者的支出/存活患者数量)以及每位患者的金钱损失(死亡患者的支出/患者总数)。
多发伤患者的中位成本为4076欧元,冠状动脉手术患者为380欧元。成本差异主要归因于ICU住院时间的不同。ALI/ARDS、非创伤性颅内出血、多发伤和急诊腹部手术患者的每位存活患者成本较高。ALI/ARDS患者的每位患者金钱损失较高,多发伤患者较低。计划性冠状动脉手术和腹部大手术以及短期住院患者的治疗成本效益最高。
ICU中不同类型患者的治疗费用差异很大。需要采取策略来控制高成本和低效益的主要决定因素。