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柑橘园施药期间人类接触氯氰菊酯的风险评估

Risk assessment of human exposure to cypermethrin during treatment of mandarin fields.

作者信息

Choi H, Moon J K, Liu K H, Park H W, Ihm Y B, Park B S, Kim J H

机构信息

School of Agricultural Biotechnology, Seoul National University, Shillim-dong, Gwanak-gu, Seoul, 151-742, Korea.

出版信息

Arch Environ Contam Toxicol. 2006 Apr;50(3):437-42. doi: 10.1007/s00244-005-1050-3. Epub 2006 Feb 24.

Abstract

The potential dermal and respiratory exposure assessment and risk assessment for applicator were performed with cypermethrin EC. The pesticide was applied on a mandarin field using a power sprayer. Gloves were used for the hand exposure assessment, mask for face, and dermal patches for the other parts of the body. Personal air monitor equipped with a XAD-2 resin was used for the respiratory exposure assessment. During the application of cypermethrin in the field, the rate of potential dermal exposure ranged from 28.1 to 58.8 mg/h. The major exposure parts were upper-arms (22.1-24.6%) and legs (thigh and shin, 28.3-29.2%) for females and thigh (21.0-46.9%) and hand (14.9-19.3%) for males. Females were exposed more than males. No exposure was detected from the respiratory monitoring. For risk assessment, the potential dermal exposure (PDE), the absorbable quantity of exposure (AQE), and the margin of safety (MOS) were calculated. Among those four risk assessments, MOS was < 1 in only trial I, which indicated any possibility of risk. However, in the others, the possibility of risk was little. Moreover, the safe work time ranged from 3.61 h to 9.69 h.

摘要

使用氯氰菊酯乳油对施药人员进行了潜在皮肤和呼吸道暴露评估及风险评估。该农药使用动力喷雾器施用于柑橘园。手部暴露评估使用手套,面部使用口罩,身体其他部位使用皮肤贴片。配备XAD - 2树脂的个人空气监测仪用于呼吸道暴露评估。在田间施用氯氰菊酯期间,潜在皮肤暴露率为28.1至58.8毫克/小时。女性的主要暴露部位是上臂(22.1 - 24.6%)和腿部(大腿和小腿,28.3 - 29.2%),男性的主要暴露部位是大腿(21.0 - 46.9%)和手部(14.9 - 19.3%)。女性的暴露程度高于男性。呼吸道监测未检测到暴露。对于风险评估,计算了潜在皮肤暴露(PDE)、可吸收暴露量(AQE)和安全系数(MOS)。在这四项风险评估中,只有试验I的MOS < 1,这表明存在任何风险可能性。然而,在其他试验中,风险可能性很小。此外,安全工作时间为3.61小时至9.69小时。

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