Song Yishu, Wu Guangxiang, Song Qingyu, Cooks R Graham, Ouyang Zheng, Plass Wolfgang R
Department of Chemistry, Purdue University, 560 Oval Dr., 47907, West Lafayette, IN, USA.
II Physikalisches Institut, Justus-Liebig-Universität Giessen, Giessen, Germany.
J Am Soc Mass Spectrom. 2006 Apr;17(4):631-639. doi: 10.1016/j.jasms.2005.12.014. Epub 2006 Feb 28.
A novel linear ion trap mass analyzer was developed using just four elongated planar electrodes, mounted in parallel, and employing an RF potential for ion trapping in the radial and axial directions. Mass analysis was achieved using the mass-selective instability scan with ion ejection in the radial direction. The performance of this new device was characterized in comparison with the 6-electrode rectilinear ion trap (RIT) from which it is derived. The 4-electrode trap gives optimum performance in an asymmetric geometry, just like the original optimized 6-electrode RIT. The strong RF fringing fields at the ends of the RF rods account for axial ion trapping without use of extra electrodes or an axial DC voltage. Field calculations and simulations have been carried out to study the trapping potential inside RITs with various configurations. Demonstrated capabilities include analysis of externally injected ions with mass resolution in excess of 1000 and a mass/charge range of 650 Th as well as tandem mass spectrometry capabilities. The geometric simplicity and performance characteristics of the 4-electrode RIT make it particularly attractive in the development of next generation miniaturized mass spectrometers.
一种新型线性离子阱质量分析仪被开发出来，它仅使用四个平行安装的细长平面电极，并利用射频电势在径向和轴向上捕获离子。通过质量选择性不稳定扫描并在径向方向上进行离子喷射来实现质量分析。与它所衍生的六电极直线型离子阱（RIT）相比，对这种新装置的性能进行了表征。四电极阱在不对称几何结构中具有最佳性能，就像最初优化的六电极RIT一样。射频杆端部的强射频边缘场可实现轴向离子捕获，而无需使用额外的电极或轴向直流电压。已经进行了场计算和模拟，以研究具有各种配置的RIT内部的捕获电势。所展示的能力包括对外部注入离子进行质量分辨率超过1000且质荷比范围为650 Th的分析以及串联质谱分析能力。四电极RIT的几何简单性和性能特点使其在下一代小型化质谱仪的开发中特别具有吸引力。
