Köhler L W, Pemberton J H, Zinsmeister A R, Kelly K A
Department of Surgery, Mayo Clinic, Rochester, Minnesota.
Gastroenterology. 1991 Sep;101(3):679-84.
Recent work has shown that patients undergoing proctocolectomy and ileal pouch-anal anastomosis experience a better quality of life than those undergoing proctocolectomy and Brooke ileostomy. To assess whether the improvement with the pouch is due to the absence of a stoma or the preservation of fecal continence, functional and performance activities were assessed in 406 patients with Brooke ileostomies (stoma present, incontinent), 313 with Kock pouches (stoma present, continent), and 298 with ileal pouch-anal anastomoses (stoma absent, continent). All patients underwent proctocolectomy for ulcerative colitis or familial adenomatous polyposis. After adjusting for age, sex, diagnosis, attitude towards the operation, dietary satisfaction, and ability to work, the likelihood of an impact on performance was estimated for the three types of operation using logistic regression analysis. Patients with ileal pouch-anal anastomoses had fewer restrictions in sports and sexual activities than those with Kock pouches (P less than 0.05), whereas those with Kock pouches in turn had fewer restrictions in these activities but more restrictions in travel than those with Brooke ileostomies (P less than 0.05). In contrast, performance in the categories of social life, recreation, work, and family was similar between groups. It is concluded that both the presence of a stoma and fecal incontinence impair the quality of life after proctocolectomy. Ileal pouch-anal anastomosis, which avoids both stoma and incontinence, offers the best quality of life between the three operations studied.
近期研究表明,接受直肠结肠切除术和回肠储袋肛管吻合术的患者比接受直肠结肠切除术和布鲁克回肠造口术的患者生活质量更高。为评估使用储袋后生活质量的改善是由于无造口还是由于保留了粪便节制功能,对406例布鲁克回肠造口术患者(有造口,大便失禁)、313例科克储袋患者(有造口,大便节制)和298例回肠储袋肛管吻合术患者(无造口,大便节制)的功能和行为活动进行了评估。所有患者均因溃疡性结肠炎或家族性腺瘤性息肉病接受了直肠结肠切除术。在对年龄、性别、诊断、对手术的态度、饮食满意度和工作能力进行校正后,使用逻辑回归分析估计了三种手术方式对行为的影响可能性。回肠储袋肛管吻合术患者在运动和性活动方面的限制比科克储袋患者少(P<0.05),而科克储袋患者在这些活动中的限制又比布鲁克回肠造口术患者少,但在旅行方面的限制更多(P<0.05)。相比之下,各组在社交生活、娱乐、工作和家庭方面的表现相似。结论是,造口的存在和大便失禁都会损害直肠结肠切除术后的生活质量。回肠储袋肛管吻合术避免了造口和失禁,在所研究的三种手术中提供了最佳的生活质量。