Si Jian-hua, Tan Jia-ju, Yang Guang, Tang Li-xia
First People's Hospital of Foshan City, Foshan 528000, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2006 Feb;26(2):220-1.
To identify patients with SARS coronavirus infection who have only mild symptoms.
Enzyme-linked immunosorbent assay was employed to detect serum antibody against SARS coronavirus in the lysate of whole SARS coronavirus from 19 SARS patients and 200 medical staff members without obvious SARS symptoms after possible exposure to the virus during routine medical practice.
Serum IgG antibody against SARS coronavirus was detected in all the 19 SARS patients, and among the 200 staff members, 20 (10%) were found positive for the antibody but with no obvious or only mild symptoms.
Serum IgG antibody against SARS coronavirus is positive in a small proportion (around 10%) of the medical staff members exposed to the virus in our hospital, but may not cause obvious symptoms, suggesting SARS coronavirus infection might in some cases have mild or even no clinical manifestations.
识别感染严重急性呼吸综合征冠状病毒（SARS冠状病毒）但仅有轻微症状的患者。
采用酶联免疫吸附试验，检测19例SARS患者以及200名在日常医疗工作中可能接触过该病毒且无明显SARS症状的医护人员血清中针对全SARS冠状病毒裂解物的抗体。
19例SARS患者血清中均检测到抗SARS冠状病毒IgG抗体，200名医护人员中，20人（10%）抗体检测呈阳性，但无明显症状或仅有轻微症状。
我院接触过该病毒的医护人员中，一小部分（约10%）血清抗SARS冠状病毒IgG抗体呈阳性，但可能未引发明显症状，这表明SARS冠状病毒感染在某些情况下可能症状轻微甚至没有临床表现。
