Feng Dan, de Vlas Sake J, Fang Li-Qun, Han Xiao-Na, Zhao Wen-Juan, Sheng Shen, Yang Hong, Jia Zhong-Wei, Richardus Jan Hendrik, Cao Wu-Chun
Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, P.R. China.
Trop Med Int Health. 2009 Nov;14 Suppl 1(Suppl 1):4-13. doi: 10.1111/j.1365-3156.2008.02145.x. Epub 2009 Jun 5.
To document and verify the number of cases of severe acute respiratory syndrome (SARS) during the 2002-2003 epidemic in mainland China.
All existing Chinese SARS data sources were integrated in one final database. This involved removing non-probable and duplicate cases, adding cases at the final stage of the outbreak, and collecting missing information.
The resulting database contains a total of 5327 probable SARS cases, of whom 343 died, giving a case fatality ratio (CFR) of 6.4%. While the total number of cases happens to be equal to the original official reports, there are 5 cases overall which did not result in death. When compared with Hong Kong Special Administrative Region of China, China Taiwan, and Singapore, the SARS epidemic in mainland China resulted in a considerably lower CFR, involved relatively younger cases and included fewer health care workers.
To optimise future data collection during large-scale outbreaks of emerging or re-emerging infectious disease, China must further improve the infectious diseases reporting system, enhance collaboration between all levels of disease control, health departments, hospitals and institutes nationally and globally, and train specialized staff working at county centres of disease control.
记录并核实2002 - 2003年中国大陆严重急性呼吸综合征（SARS）疫情期间的病例数。
将所有现有的中国SARS数据源整合到一个最终数据库中。这包括剔除疑似病例和重复病例，在疫情末期补充病例，并收集缺失信息。
最终数据库共包含5327例疑似SARS病例，其中343例死亡，病死率为6.4%。虽然病例总数与最初的官方报告一致，但总体上有5例未导致死亡。与中国香港特别行政区、中国台湾地区和新加坡相比，中国大陆的SARS疫情病死率低得多，涉及的病例相对年轻，医护人员也较少。
为在新发或再发传染病大规模暴发期间优化未来数据收集工作，中国必须进一步完善传染病报告系统，加强国家和全球各级疾病控制部门、卫生部门、医院和机构之间的协作，并培训在县级疾病控制中心工作的专业人员。
