Burmeister P, Simon A
Dtsch Med Wochenschr. 1975 May 16;100(20):1132-5. doi: 10.1055/s-0028-1106347.
A secondary Cushing's syndrome developed in a 38-year-old woman from an ACTH secreting phaeochromocytoma. Large amounts of ACTH were demonstrated in the tumour by radioimmunological tests. A remarkable feature was that clinical and biochemical signs of increased catecholamine secretion completely regressed with time and the adrenals were stimulated at intervals by the ectopic ACTH secretion, steroid excretion falling to normal in between.
一名38岁女性因分泌促肾上腺皮质激素(ACTH)的嗜铬细胞瘤引发了继发性库欣综合征。放射免疫检测显示肿瘤中存在大量ACTH。一个显著特征是,随着时间推移,儿茶酚胺分泌增加的临床和生化体征完全消退,异位ACTH分泌间歇性刺激肾上腺,其间类固醇排泄降至正常水平。