用于预防下颌第三磨牙手术中干槽症的肺泡内洗必泰凝胶。一项初步研究。

Intra-alveolar chlorhexidine gel for the prevention of dry socket in mandibular third molar surgery. A pilot study.

作者信息

Torres-Lagares Daniel, Infante-Cossio Pedro, Gutierrez-Perez Jose Luis, Romero-Ruiz Manuel Maria, Garcia-Calderon Manuel, Serrera-Figallo Maria Angeles

机构信息

Faculty of Odontology, University of Seville, Sevilla, Spain.

出版信息

Med Oral Patol Oral Cir Bucal. 2006 Mar 1;11(2):E179-84.

DOI:
Abstract

PURPOSE

Chlorhexidine is a good prophylactic agent for post-extraction dry socket alveolitis. The bio-adhesive 0.2% chlorhexidine gel could improve this action since its intra-alveolar positioning would allow a more direct action on the alveolus and more prolonged action of the medication.

MATERIALS AND METHOD

We present a single blind, randomised study on 30 patients to evaluate the efficacy of the bio-adhesive 0.2% chlorhexidine gel, placed only once within the alveolus, on the reduction of the incidence of impacted third molar post-extraction dry socket alveolitis and its post-operative effects on patients.

RESULTS

A reduction of 42.65% in the occurrence of alveolitis and a more favourable post-operative period in the experimental group was observed. In the control group, the appearance of alveolitis was 30.76% opposite to 17.64 % in the experimental group.

CONCLUSIONS

The bio-adhesive 0.2% chlorhexidine gel, applied only once after the extraction of impacted third molars, seems to be an appropriate option for the reduction of alveolitis. It improves the buccal aperture and oedema in the post-operative period, although further double blind studies with larger samples are necessary.

摘要

目的

氯己定是预防拔牙后干槽症的良好药物。生物黏附性0.2%氯己定凝胶可增强这一作用,因为其在牙槽内的定位能使其对牙槽发挥更直接的作用,且药物作用时间更持久。

材料与方法

我们对30例患者进行了一项单盲随机研究,以评估仅在牙槽内放置一次的生物黏附性0.2%氯己定凝胶在降低阻生第三磨牙拔牙后干槽症发生率及其对患者术后影响方面的疗效。

结果

观察到实验组牙槽炎发生率降低了42.65%,且术后恢复情况更佳。对照组牙槽炎发生率为30.76%,而实验组为17.64%。

结论

阻生第三磨牙拔除后仅应用一次的生物黏附性0.2%氯己定凝胶似乎是降低牙槽炎的合适选择。它能改善术后颊部开口度和水肿情况,不过仍需进一步开展更大样本量的双盲研究。

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