[聚氯乙烯（PCV）与磺胺胍（SV）加维生素A（A）治疗十二指肠溃疡疗效的临床研究及长期随访观察]

[Clinical study and long-term follow-up observations on the effect of PCV and SV+A in the treatment of duodenal ulcer].

作者信息

Zou Z

出版信息

Zhonghua Yi Xue Za Zhi. 1991 Apr;71(4):213-6, 16.

Abstract

From Aug. 1977 to June 1988, vagotomy had been performed in 238 patients with duodenal ulcer (DU). According to the clinical signs and the result of gastric acid secretion test, (GAST) parietal cell vagotomy (PCV) and selective vagotomy plus antrectomy (SV+A) were performed in 100 and 138 cases respectively. The patients were followed up for 1 to 10 years. 96% and 97% of them belonged to Visick grade I and II respectively. The recurrence rate was 1.96% in PCV group, while no ulcer recurrence was seen in SV+A group, long-term side effect was rare and the nutritional status was quite good. The follow-up data showed that recurrence rate could be greatly reduced if the mode of vagotomy was selected according to results of GAST.

摘要

1977年8月至1988年6月，对238例十二指肠溃疡（DU）患者实施了迷走神经切断术。根据临床体征和胃酸分泌试验（GAST）结果，分别对100例和138例患者实施了壁细胞迷走神经切断术（PCV）和选择性迷走神经切断术加胃窦切除术（SV+A）。对患者进行了1至10年的随访。其中分别有96%和97%的患者属于Visick I级和II级。PCV组的复发率为1.96%，而SV+A组未见溃疡复发，长期副作用少见且营养状况良好。随访数据表明，根据GAST结果选择迷走神经切断术方式可大大降低复发率。