Petermann J, Rosenbaum K D, Panzig E
Zentralbl Chir. 1982;107(4):200-6.
The course of gastric acid secretion and serum gastrin level before and after operation was studied in 41 patients suffering from a gastroscopically determined ulcer disease. In 15 patients suffering from duodenal ulcer, a highly selective vagotomy without pyloroplasty was performed and in 26 patients suffering from peptic ulcer (duodenal or gastric ulcer) a partial gastrectomy (Billroth I). After a highly selective vagotomy without pyloroplasty a reduction in the secretory response to pentagastrin and a significant rise of the basic and postprandial gastrin concentration could be observed. Both methods are suitable to determine the completeness of vagotomy. The estimation of the course of serum gastrin level after vagotomy only reveals a temporary disorder of the antrum-pylorus mechanism. In our opinion a pyloroplasty is not necessary.
对41例经胃镜确诊为溃疡病的患者，研究了手术前后胃酸分泌过程及血清胃泌素水平。对15例十二指肠溃疡患者行高选择性迷走神经切断术而未做幽门成形术，对26例消化性溃疡（十二指肠溃疡或胃溃疡）患者行胃部分切除术（毕罗一世式）。行高选择性迷走神经切断术而未做幽门成形术后，可观察到对五肽胃泌素的分泌反应降低，基础及餐后胃泌素浓度显著升高。这两种方法均适用于确定迷走神经切断术的完整性。迷走神经切断术后血清胃泌素水平变化的评估仅显示胃窦-幽门机制的暂时紊乱。我们认为没有必要做幽门成形术。
