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壁细胞迷走神经切断术与选择性迷走神经切断术加胃窦切除术治疗十二指肠溃疡。10年随访

Parietal cell vagotomy and selective vagotomy plus antrectomy in the treatment of duodenal ulcer. A follow-up of 10 years.

作者信息

Zou Z S, Li J S, Li N

机构信息

General Hospital of Nanjing Unit, PLA.

出版信息

Chin Med J (Engl). 1991 Feb;104(2):103-8.

PMID:1874007
Abstract

Two hundred and thirty-eight patients with duodenal ulcer were subjected to vagotomy. According to the clinical manifestations and the results of gastric acid secretion test, parietal cell vagotomy was done in 100 patients and selective vagotomy plus antrectomy in 138 patients. Follow-up after operation for 10 years showed that 96% and 97% of patients belonged to Visick Grade I and II respectively. The recurrence rate for parietal cell vagotomy was 1.96%, but no recurrence was seen in the group of selective vagotomy plus antrectomy. Long-term side-effects were rarely found in the patients. They had good nutritional states. The follow-up data showed that the recurrence rate could be greatly reduced if the modality of vagotomy was selected according to the type of gastric acid secretion test. The importance of surgeons experience and careful manipulation was emphasized.

摘要

238例十二指肠溃疡患者接受了迷走神经切断术。根据临床表现和胃酸分泌试验结果,100例行壁细胞迷走神经切断术,138例行选择性迷走神经切断术加胃窦切除术。术后随访10年显示,分别有96%和97%的患者属于Visick I级和II级。壁细胞迷走神经切断术的复发率为1.96%,但选择性迷走神经切断术加胃窦切除术组未见复发。患者很少出现长期副作用。他们营养状况良好。随访数据表明,根据胃酸分泌试验类型选择迷走神经切断术方式可大大降低复发率。强调了外科医生经验和仔细操作的重要性。

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