Benassai G, Mastrorilli M, Quarto G, Galloro G, Cantelmo A, Esposito T
Department of General, Oncological and Videoassisted Surgery, University of Naples Federico II, School of Medicine, Italy.
Hepatogastroenterology. 2006 Jan-Feb;53(67):77-81.
BACKGROUND/AIMS: During the past decade, the development of mini-invasive surgery has determined a resurgence in popularity of the antireflux surgery. The purpose of this study is to examine indications, preoperative evaluation, surgical techniques, and outcomes after mini-invasive surgery.
From 1996 to 2000, 25 patients with gastroesophageal reflux disease associated to hiatal hernia underwent laparoscopic surgery. The indication for surgery was failure of long-term medical therapy. All patients had severe acid reflux on 24h-pH monitoring, endoscopic evidence of esophagitis, and defective lower esophageal sphincter. Nissen fundoplication was performed in 16 patients with normal esophageal body motility, and 270 degrees posterior fundoplication in 9 patients with low esophageal motility.
Mortality and conversion rate were 0. Mean operative time was 130 minutes and mean postoperative hospital stay 5 days. Twenty-four (96%) patients were completely cured of reflux symptoms off all medications. Transient, mild postoperative dysphagia occurred in 3 patients (12%). There was a significant improvement of the results in postoperative esophageal manometry and 24h-pH monitoring.
Despite the fact that few patients were treated by using laparoscopic approach, results are encouraging with less morbidity and great advantages for patients. Precise selection of patients and surgical techniques are essential.
背景/目的:在过去十年中,微创手术的发展使得抗反流手术再度流行起来。本研究的目的是探讨微创手术的适应证、术前评估、手术技术及术后效果。
1996年至2000年,25例患有与食管裂孔疝相关的胃食管反流病患者接受了腹腔镜手术。手术适应证为长期药物治疗失败。所有患者24小时pH监测显示有严重的酸反流,内镜检查有食管炎证据,且食管下括约肌功能不全。16例食管体部蠕动正常的患者行nissen胃底折叠术,9例食管蠕动功能低下的患者行270度后胃底折叠术。
死亡率和中转开腹率均为0。平均手术时间为130分钟,平均术后住院时间为5天。24例(96%)患者停用所有药物后反流症状完全治愈。3例患者(12%)出现短暂、轻度的术后吞咽困难。术后食管测压和24小时pH监测结果有显著改善。
尽管采用腹腔镜手术治疗的患者数量较少,但结果令人鼓舞,并发症较少,对患者有很大优势。精确选择患者和手术技术至关重要。