Langer David J, Song Joon K, Niimi Yasunari, Chwajol Markus, Lefton Daniel R, Brisman Jonathan L, Molofsky Walter, Kupersmith Mark J, Berenstein Alejandro
Department of Neurosurgery, Hyman-Newman Institute for Neurology and Neurosurgery, Roosevelt Hospital, New York, New York 10019, USA.
J Neurosurg. 2006 Jan;104(1 Suppl):41-5. doi: 10.3171/ped.2006.104.1.41.
In patients with vein of Galen malformations, high-flow shunting decreases cerebral perfusion. By reducing or eliminating these shunts, transarterial embolization can improve cerebral perfusion and clinical outcomes. Quantifying pre- and postembolization shunt blood flow may help determine the optimal timing and efficacy of embolization and may provide prognostic information. The authors used magnetic resonance imaging noninvasive optimal vessel analysis as a novel modality to measure volumetric blood flow through vein of Galen malformation shunts in a neonate and an infant before and after transarterial embolization.