循环抗体与呼吸道病毒感染。
Circulating antibodies and respiratory virus infections.
作者信息
Tyrrell D A
出版信息
Dev Biol Stand. 1975;28:152-8.
PMID:165114
Abstract
Most respiratory viruses infect only the respiratory mucosa and mainly the surface epithelium, and it is therefore plausible that antibody within the circulation is unable to influence them, either by preventing infection or by terminating it once it has started. However there is experimental and observational evidence that some infections are prevented by circulating antibody. This may be because circulating immunoglobulins are released onto the surface possibly because of virus cytopathic effects or hypersensitivity to a viral antigen.
摘要
大多数呼吸道病毒仅感染呼吸道黏膜，主要是表面上皮细胞，因此循环抗体不太可能通过预防感染或在感染一旦开始后就终止感染来影响这些病毒。然而，有实验和观察证据表明，循环抗体可预防某些感染。这可能是因为循环免疫球蛋白可能由于病毒的细胞病变效应或对病毒抗原的超敏反应而释放到表面。
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