• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Post-metalation structural insights into the use of alkali-metal-mediated zincation for directed ortho-metalation of a tertiary aromatic amide.

作者信息

Clegg William, Dale Sophie H, Harrington Ross W, Hevia Eva, Honeyman Gordon W, Mulvey Robert E

机构信息

School of Natural Sciences (Chemistry), University of Newcastle, Newcastle upon Tyne, NE1 7RU, UK.

出版信息

Angew Chem Int Ed Engl. 2006 Apr 3;45(15):2374-7. doi: 10.1002/anie.200503213.

DOI:10.1002/anie.200503213
PMID:16511892
Abstract
摘要

相似文献

1
Post-metalation structural insights into the use of alkali-metal-mediated zincation for directed ortho-metalation of a tertiary aromatic amide.碱金属介导的锌化用于叔芳酰胺定向邻位金属化的金属化后结构见解。
Angew Chem Int Ed Engl. 2006 Apr 3;45(15):2374-7. doi: 10.1002/anie.200503213.
2
Pre-metalation structural insights into the use of alkali-metal-mediated zincation for directed ortho-metalation of a tertiary aromatic amide.预金属化结构见解：关于碱金属介导的锌化用于叔芳酰胺定向邻位金属化的研究
Angew Chem Int Ed Engl. 2006 Apr 3;45(15):2370-4. doi: 10.1002/anie.200503202.
3
Directed meta-metalation using alkali-metal-mediated zincation.使用碱金属介导的锌化进行定向间位金属化
Angew Chem Int Ed Engl. 2006 Jun 2;45(23):3775-8. doi: 10.1002/anie.200600720.
4
Alkali-metal-mediated zincation of anisole: synthesis and structures of three instructive ortho-zincated complexes.碱金属介导的苯甲醚锌化反应：三种具有指导意义的邻位锌化配合物的合成与结构
J Am Chem Soc. 2006 Jun 14;128(23):7434-5. doi: 10.1021/ja061898g.
5
New reactivity and structural insights of alkali-metal-mediated alumination in directed ortho-alumination of a tertiary aromatic amide.叔芳酰胺定向邻位铝化反应中碱金属介导的铝化反应的新反应活性及结构见解
Chem Commun (Camb). 2006 Aug 14(30):3208-10. doi: 10.1039/b606080c. Epub 2006 Jun 19.
6
Avant-garde metalating agents: structural basis of alkali-metal-mediated metalation.前沿金属化试剂：碱金属介导金属化的结构基础。
Acc Chem Res. 2009 Jun 16;42(6):743-55. doi: 10.1021/ar800254y.
7
First general, direct, and regioselective synthesis of substituted methoxybenzoic acids by ortho metalation.通过邻位金属化首次实现取代甲氧基苯甲酸的通用、直接和区域选择性合成。
J Org Chem. 2007 Apr 27;72(9):3419-29. doi: 10.1021/jo070082a. Epub 2007 Mar 29.
8
Directed ortho metalation-cross coupling strategies. N-cumyl arylsulfonamides. Facile deprotection and expedient route to 7- and 4,7-substituted saccharins.定向邻位金属化-交叉偶联策略。N-（对异丙基苯基）芳基磺酰胺。7-和4,7-取代糖精的简便脱保护及便捷合成路线。
J Org Chem. 2007 Apr 27;72(9):3199-206. doi: 10.1021/jo062385v. Epub 2007 Mar 27.
9
Regiocontrolled deprotonative-zincation of bromopyridines using aminozincates.使用氨基锌酸盐对溴吡啶进行区域控制的去质子化锌化反应。
Chem Commun (Camb). 2001 Dec 7(23):2450-1.
10
Alkali-Metal-Alkoxide Powered Zincation of Fluoroarenes Employing Zinc Bis-Amide Zn(TMP).碱金属醇盐助力锌试剂 Zn(TMP)实现氟代芳烃的锌化反应
Angew Chem Int Ed Engl. 2023 Jul 17;62(29):e202303099. doi: 10.1002/anie.202303099. Epub 2023 Jun 7.

引用本文的文献

1
Arene Activation by Calcium Hydride/Zinc Amide Equilibration.通过氢化钙/锌酰胺平衡实现芳烃活化
J Am Chem Soc. 2025 Aug 13;147(32):29554-29567. doi: 10.1021/jacs.5c10735. Epub 2025 Aug 2.
2
Heavy Alkali Metal Manganate Complexes: Synthesis, Structures and Solvent-Induced Dissociation Effects.重碱金属锰酸盐配合物：合成、结构及溶剂诱导解离效应
Chemistry. 2022 Oct 4;28(55):e202201716. doi: 10.1002/chem.202201716. Epub 2022 Aug 3.
3
Main group bimetallic partnerships for cooperative catalysis.用于协同催化的主要主族双金属组合
Chem Sci. 2020 Oct 16;12(6):1982-1992. doi: 10.1039/d0sc05116k.
4
Structural Motifs of Alkali Metal Superbases in Non-coordinating Solvents.非配位溶剂中碱金属超强碱的结构基序
Chemistry. 2021 Jan 13;27(3):888-904. doi: 10.1002/chem.202002812. Epub 2020 Nov 9.
5
Site-Selective Copper-Catalyzed Amination and Azidation of Arenes and Heteroarenes via Deprotonative Zincation.通过去质子化锌化实现芳基和杂芳基的位点选择性铜催化胺化和叠氮化反应。
J Am Chem Soc. 2017 Aug 23;139(33):11622-11628. doi: 10.1021/jacs.7b07661. Epub 2017 Aug 14.
6
Copper-catalyzed electrophilic amination of heteroarenes and arenes by C-H zincation.通过C-H锌化实现铜催化的杂芳烃和芳烃的亲电胺化反应。
Angew Chem Int Ed Engl. 2014 Apr 25;53(18):4667-70. doi: 10.1002/anie.201311029. Epub 2014 Mar 25.
7
Evaluating cis-2,6-dimethylpiperidide (cis-DMP) as a base component in lithium-mediated zincation chemistry.评估顺-2,6-二甲基哌啶（cis-DMP）作为锂介导的锌化反应中的基础组分。
Chemistry. 2013 Sep 27;19(40):13492-503. doi: 10.1002/chem.201301180. Epub 2013 Aug 19.
8
Meta-metallation of N,N-dimethylaniline: Contrasting direct sodium-mediated zincation with indirect sodiation-dialkylzinc co-complexation.N,N-二甲基苯胺的间位金属化：直接的钠介导锌化与间接的钠-二烷基锌共络合的对比。
Beilstein J Org Chem. 2011;7:1234-48. doi: 10.3762/bjoc.7.144. Epub 2011 Sep 6.
9
Main group multiple C-H/N-H bond activation of a diamine and isolation of a molecular dilithium zincate hydride: experimental and DFT evidence for alkali metal-zinc synergistic effects.二胺的主族多 C-H/N-H 键活化及分子二锂锌氢化盐的分离：碱金属-锌协同效应的实验和 DFT 证据。
J Am Chem Soc. 2011 Aug 31;133(34):13706-17. doi: 10.1021/ja205547h. Epub 2011 Aug 4.
10
Structural basis for regioisomerization in the alkali-metal-mediated zincation (AMMZn) of trifluoromethyl benzene by isolation of kinetic and thermodynamic intermediates.碱金属促进的三氟甲基苯锌化（AMMZn）反应中区域异构体形成的结构基础：动力学和热力学中间体的分离。
J Am Chem Soc. 2010 Jul 14;132(27):9480-7. doi: 10.1021/ja1038598.