Van Thiel D H, deBelle R C, Painter T D, McMillan W B, Haradin A R
Gastroenterology. 1975 May;68(5 Pt 1):1292-6.
Phytobezoar occurring as a complication of gastric carcinoma is reported for the first time. A review of the pathogenesis of phytobezoar suggests that hypomotility and hyposecretion are the two most important factors in bezoar formation. In the case discussed, hypomotility as a consequence of neoplastic involvement of the gastric antrum was the most important precipitating factor. However, documentation of prior hyposecretion was also noted and suggests that a combination of these two factors may be more significant than each taken alone. The therapeutic management of bezoars in patients who are not candidates for surgery is frequently difficult. This is the third case in which the enzyme cellulase has been used successfully for bezoar dissolution.
首次报道了作为胃癌并发症出现的植物性胃石。对植物性胃石发病机制的回顾表明,胃动力不足和分泌减少是胃石形成的两个最重要因素。在所讨论的病例中,胃窦肿瘤累及导致的胃动力不足是最重要的促发因素。然而,也注意到有先前分泌减少的记录,这表明这两个因素的结合可能比单独任何一个因素更具重要性。对于不适合手术的患者,胃石的治疗管理通常很困难。这是第三例成功使用纤维素酶溶解胃石的病例。