• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

环磷酸腺苷与体外脱氧核糖核酸合成的抑制

Cyclic adenosine 3':5'-monophosphate and inhibition of deoxyribonucleic acid synthesis in vitro.

作者信息

Rytömaa T, Kiviniemi K

出版信息

In Vitro. 1975 Jan-Feb;11(1):1-4. doi: 10.1007/BF02615315.

DOI:10.1007/BF02615315
PMID:165140
Abstract

Results are presented which suggest that inhibition of tritiated thymidine incorporation into the deoxyribonucleic acid of bone marrow in vitro by high concentrations of cyclic adenosine 3':5'-monophosphate is pharmacological in nature, and thus apparently unrelated to the physiological actions of cAMP.

摘要

研究结果表明，高浓度的环磷腺苷 3':5'-单磷酸在体外抑制氚标记胸腺嘧啶核苷掺入骨髓脱氧核糖核酸的作用本质上是药理学作用，因此显然与环磷腺苷的生理作用无关。

相似文献

1
Cyclic adenosine 3':5'-monophosphate and inhibition of deoxyribonucleic acid synthesis in vitro.环磷酸腺苷与体外脱氧核糖核酸合成的抑制
In Vitro. 1975 Jan-Feb;11(1):1-4. doi: 10.1007/BF02615315.
2
Studies of effects of cyclic adenosine 3',5'-monophosphate in regulation of human hemopoiesis in vitro.3',5'-环磷酸腺苷在体外调节人类造血作用的研究。
In Vitro. 1973 Sep-Oct;9(2):86-91. doi: 10.1007/BF02616005.
3
Enhancement of DNA synthesis of mouse myelogenous cells by cyclic adenosine 3',5'-monophosphate (cAMP).3',5'-环磷酸腺苷（cAMP）对小鼠骨髓细胞DNA合成的增强作用。
Acta Med Okayama. 1974 Apr;28(2):81-7.
4
Biochemical aspects of cardiac muscle differentiation. Possible control of deoxyribonucleic acid synthesis and cell differentiation by adrenergic innervation and cyclic adenosine 3':5'-monophosphate.心肌分化的生化方面。肾上腺素能神经支配和环磷酸腺苷对脱氧核糖核酸合成及细胞分化的可能调控。
J Biol Chem. 1976 Oct 10;251(19):6082-9.
5
Divergent action mechanism of cAMP and dibutyryl cAMP on cell proliferation and macromolecular synthesis in HeLa S3 cultures.环磷酸腺苷（cAMP）和二丁酰环磷酸腺苷（dibutyryl cAMP）对HeLa S3培养物中细胞增殖和大分子合成的不同作用机制
Mol Cell Biochem. 1973 Jun 27;1(2):229-39. doi: 10.1007/BF01659332.
6
Regulation of DNA synthesis by guanosine-5'-diphosphate, cyclic guanosine-3',5'-monophosphate, and cyclic adenosine-3', 5'-monophosphate in mouse lymphoid cells.鸟苷-5'-二磷酸、环鸟苷-3',5'-单磷酸和环腺苷-3',5'-单磷酸对小鼠淋巴细胞中DNA合成的调节
Exp Cell Res. 1975 Jul;93(2):309-14. doi: 10.1016/0014-4827(75)90455-3.
7
Stimulation of ribonucleic acid synthesis in horse lymphocyte by exogenous cyclic adenosine 3',5'-monophosphate.外源性3',5'-环磷酸腺苷对马淋巴细胞核糖核酸合成的刺激作用。
J Biol Chem. 1972 Jan 25;247(2):413-7.
8
Chemotactic responses of human polymorphonuclear leukocytes to cyclic GMP and other compounds.人多形核白细胞对环磷酸鸟苷及其他化合物的趋化反应。
Exp Cell Res. 1974 Jul;87(1):1-7. doi: 10.1016/0014-4827(74)90519-9.
9
Effects of cyclic nucleotides on deoxyribonucleic acid synthesis in hypophysectomized rat cartilage: stimulation of thymidine incorporation and potentiation of the action of somatomedin by analogs of adenosine 3',5'-monophosphate or a cyclic nucleotide phosphodiesterase inhibitor.环核苷酸对垂体切除大鼠软骨中脱氧核糖核酸合成的影响：3',5'-单磷酸腺苷类似物或环核苷酸磷酸二酯酶抑制剂刺激胸苷掺入并增强生长激素介质的作用。
Endocrinology. 1980 Aug;107(2):626-32. doi: 10.1210/endo-107-2-626.
10
Effect of cyclic nucleotides on DNA synthesis in mouse lymphoid cells.环核苷酸对小鼠淋巴细胞DNA合成的影响。
Immunol Commun. 1975;4(1):51-62. doi: 10.3109/08820137509055761.

引用本文的文献

1
Molecular weight and some chemical properties of the granulocytic chalone.
Blut. 1978 Jul 14;37(1):7-18. doi: 10.1007/BF01006548.

本文引用的文献

1
Tissue culture screening of purines and purine nucleosides for selective damage to mouse sarcoma cells.嘌呤和嘌呤核苷对小鼠肉瘤细胞选择性损伤的组织培养筛选
Cancer Res. 1952 Jun;12(6):399-406.
2
Pyrimidine starvation induced by adenosine in fibroblasts and lymphoid cells: role of adenosine deaminase.腺苷在成纤维细胞和淋巴细胞中诱导的嘧啶饥饿：腺苷脱氨酶的作用
Science. 1973 Nov 23;182(4114):836-7. doi: 10.1126/science.182.4114.836.
3
Studies of effects of cyclic adenosine 3',5'-monophosphate in regulation of human hemopoiesis in vitro.
3',5'-环磷酸腺苷在体外调节人类造血作用的研究。
In Vitro. 1973 Sep-Oct;9(2):86-91. doi: 10.1007/BF02616005.
4
Drug receptors and the haemopoietic stem cell.药物受体与造血干细胞
Nat New Biol. 1973 Jan 31;241(109):152-4. doi: 10.1038/newbio241152a0.
5
The ability of calcium to change cyclic AMP from a stimulator to an inhibitor to thymic lymphoblast proliferation.钙将环磷酸腺苷从胸腺淋巴母细胞增殖的刺激物转变为抑制剂的能力。
J Cell Physiol. 1973 Apr;81(2):241-50. doi: 10.1002/jcp.1040810212.
6
Inhibition of replication in functional mouse adrenal tumor cells by adrenocorticotropic hormone mediated by adenosine 3':5'-cyclic monophosphate.促肾上腺皮质激素通过3':5'-环磷酸腺苷介导对功能性小鼠肾上腺肿瘤细胞复制的抑制作用。
Proc Natl Acad Sci U S A. 1971 Dec;68(12):3206-10. doi: 10.1073/pnas.68.12.3206.
7
Restoration of contact-inhibited growth to transformed cells by dibutyryl adenosine 3':5'-cyclic monophosphate.二丁酰腺苷 3':5'-环磷酸酯使转化细胞恢复接触抑制生长。
Proc Natl Acad Sci U S A. 1971 Jun;68(6):1316-20. doi: 10.1073/pnas.68.6.1316.
8
Stimulation of DNA synthesis and mitotic activity of thymic lymphocytes by cyclic adenosine 3'5'-monophosphate.3',5'-环磷酸腺苷对胸腺淋巴细胞DNA合成及有丝分裂活性的刺激作用。
Exp Cell Res. 1969 Nov;58(1):188-91. doi: 10.1016/0014-4827(69)90135-9.
9
Effects of prostaglandins, epinephrine and NaF on human leukocyte, platelet and liver adenyl cyclase.
Blood. 1970 Apr;35(4):514-6.
10
Cyclic nucleotides on cell growth in vitro.
Cancer Res. 1970 Feb;30(2):376-8.