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[主动脉十二指肠瘘作为胃肠道出血的病因——内镜诊断的困难]

[Aortoduodenal fistula as a cause of gastrointestinal bleeding--difficulties in endoscopic diagnosis].

作者信息

Probst A, Bittinger M, Eberl T, Jakob R, Zinkl K, Heiss A, Eser R, Häckel T, Messmann H

机构信息

III. Medizinische Klinik, Klinikum Augsburg.

出版信息

Z Gastroenterol. 2006 Mar;44(3):239-44. doi: 10.1055/s-2006-926490.

Abstract

We report on three patients with severe gastrointestinal bleeding arising from aortoenteric fistula. Two patients presented with a secondary aortoduodenal fistula. In the first case bleeding occurred 8 months after aortobifemoral graft implantation. In the second patient aortobiliacal graft implantation was performed 22 years before. In the third case the aortoenteric fistula was primary and was caused by an abdominal aortic aneurysm without prior vascular intervention. In the first case diagnosis was made by urgent endoscopy visualizing ongoing bleeding from the duodenal fistula. In the two other patients urgent endoscopy and CT as well could not demonstrate the bleeding source. Aortoenteric fistula was diagnosed endoscopically during severe rebleeding some hours later. Two patients underwent surgery with implantation of an axillobifemoral bypass; the third patient declined further intervention and died. The course shows that aortoduodenal fistula can present with severe but intermittent gastrointestinal bleeding making the diagnosis in the non-bleeding interval difficult. In patients with severe gastrointestinal bleeding and a history of aortic disease (aneurysm, prior aortic graft repair or stenting) an aortoduodenal fistula should be suspected and the indication for surgical intervention should be considered early in spite of negative results of endoscopy and CT.

摘要

我们报告了3例因主动脉肠瘘导致严重胃肠道出血的患者。2例患者表现为继发性主动脉十二指肠瘘。第一例患者在主动脉双股动脉移植术后8个月出现出血。第二例患者在22年前进行了主动脉髂动脉移植术。第三例患者的主动脉肠瘘为原发性,由腹主动脉瘤引起,之前未进行过血管干预。第一例患者通过紧急内镜检查确诊,可见十二指肠瘘持续出血。另外2例患者的紧急内镜检查和CT均未能显示出血源。数小时后,在严重再次出血期间通过内镜检查诊断出主动脉肠瘘。2例患者接受了手术,植入腋双股动脉旁路;第三例患者拒绝进一步干预并死亡。病程表明,主动脉十二指肠瘘可表现为严重但间歇性的胃肠道出血,在无出血间期难以诊断。对于有严重胃肠道出血且有主动脉疾病史(动脉瘤、既往主动脉移植修复或支架置入)的患者,尽管内镜检查和CT结果为阴性,仍应怀疑主动脉十二指肠瘘,并应尽早考虑手术干预的指征。

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