Vyas V, Rammah A M A, Ashebu S D, Sharaan G M, El-Sayed M, Jarslov N, El-Khodary A
Department of Medical Oncology, Kuwait Cancer Control Center, Kuwait City, Kuwait.
Int J Gynecol Cancer. 2006 Jan-Feb;16 Suppl 1:349-52. doi: 10.1111/j.1525-1438.2006.00485.x.
Primary osteosarcoma is one of the rare tumors affecting ovaries. This case is being reported for its rarity, along with a review of the literature. In this study, the patient, a 43-year-old woman, presented with an abdominopelvic mass. Exploratory laparotomy was performed, which revealed an extensive left ovarian mass infiltrating the uterus, small bowel, and urinary bladder. Subtotal hysterectomy and small bowel resection followed by end-to-end anastomosis and bilateral salpingo-ophorectomy were performed. Histopathology showed primary osteosarcoma of the ovary. Eighteen days after surgery, she started presenting with progressive abdominal distention and ultimately developed subacute intestinal obstruction. She was started on carboplatin and epirubicin combination but failed to respond and died of fast progressive disease. It is concluded that primary osteosarcoma of the ovary is a rare disease with poor prognosis.
