Eltabbakh G H, Belinson J L, Biscotti C V
Department of Gynecology, Cleveland Clinic Foundation, Ohio, USA.
Int J Gynecol Pathol. 1997 Jan;16(1):76-8. doi: 10.1097/00004347-199701000-00012.
A 23-year-old black woman presented with abdominal pain of sudden onset, high fever, chills, and an elevated serum alkaline phosphatase level. Examination revealed a tender abdominopelvic mass consistent with an ovarian mass. Her medical history was significant for an osteosarcoma of the left humerus removed 7 years earlier and excision of multiple pulmonary and chest wall metastases 2 years earlier. Exploratory laparotomy revealed a solid hemorrhagic left ovarian mass and ascites. There was no other evidence of disease. A left salpingo-oophorectomy was performed. Pathological examination of the mass showed metastatic osteosarcoma. Four months later, the patient died of widespread osteosarcoma. The clinicopathologic features of ovarian osteogenic sarcomas reported in the literature are reviewed. Pain, fever, and elevated serum alkaline phosphatase levels may be the presenting clinical features of this rare ovarian tumor.
一名23岁黑人女性因突发腹痛、高热、寒战以及血清碱性磷酸酶水平升高前来就诊。检查发现下腹盆腔有压痛性肿块，与卵巢肿块相符。她的病史包括7年前左肱骨骨肉瘤切除术以及2年前多处肺和胸壁转移灶切除术。剖腹探查发现左侧卵巢有实性出血性肿块及腹水。无其他疾病证据。遂行左侧输卵管卵巢切除术。肿块病理检查显示为转移性骨肉瘤。4个月后，患者死于广泛转移的骨肉瘤。本文回顾了文献中报道的卵巢骨肉瘤的临床病理特征。疼痛、发热和血清碱性磷酸酶水平升高可能是这种罕见卵巢肿瘤的主要临床特征。
