X染色体与常染色体之间的平衡行为。
A balancing act between the X chromosome and the autosomes.
作者信息
Cheng Mimi K, Disteche Christine M
机构信息
Department of Pathology, University of Washington, Seattle, WA 98195, USA.
出版信息
J Biol. 2006;5(1):2. doi: 10.1186/jbiol32. Epub 2006 Feb 16.
Abstract
Dosage compensation equalizes gene dosage between males and females, but its role in balancing expression between the X chromosome and the autosomes may be far more important. Now, DNA microarrays have shown equality between the average expression of X-linked genes and that of autosomal genes, in male and female tissues of flies, worms and mice.
摘要
剂量补偿使雄性和雌性之间的基因剂量相等，但其在平衡X染色体和常染色体之间的表达方面的作用可能更为重要。现在，DNA微阵列已显示，在果蝇、蠕虫和小鼠的雄性和雌性组织中，X连锁基因的平均表达与常染色体基因的平均表达相等。
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