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飞秒激光制瓣后短暂性光敏感:临床发现与处理

Transient light sensitivity after femtosecond laser flap creation: clinical findings and management.

作者信息

Stonecipher Karl G, Dishler Jon G, Ignacio Teresa S, Binder Perry S

机构信息

Southeastern Laser and Refractive Center, Greensboro, North Carolina, USA.

出版信息

J Cataract Refract Surg. 2006 Jan;32(1):91-4. doi: 10.1016/j.jcrs.2005.11.015.

Abstract

PURPOSE

To describe the constellation of subjective and objective findings associated with unusual occurrences of photosensitivity after laser in situ keratomileusis (LASIK) with femtosecond flap creation and identify optimal management strategies.

METHODS

Demographic data, laser settings, subjective complaints, clinical findings, treatment, and response to treatment were recorded for suspected cases of transient postoperative photosensitivity from 3 surgeons operating at 3 different sites. All cases were estimated for the period covering the suspected cases at each site to assess incidence. Additional cases were solicited from IntraLase users via a survey.

RESULTS

For the 3 sites, 63 eyes from 33 patients were reported of a total estimated case log of 5667 (incidence, 1.1%). Average age was 41 years, and 51.7% of patients were women. Onset of symptoms ranged from 2 to 6 weeks after uneventful LASIK. All patients were treated with prednisolone acetate drops, whereas 1 surgeon also used Restasis (cyclosporine ophthalmic solution 0.05%). Patients noted improvement of symptoms within 1 week of treatment. When the raster and side-cut energy settings were lowered (by an average of 24% and 33%, respectively), significant reductions in incidence were noted. Similar findings were reported by 3 additional surgeons reporting 17 cases in the survey of IntraLase users.

CONCLUSIONS

This report describes a new complication of LASIK performed with a femtosecond laser keratome that may be related to the pulse energy used for flap creation. Although there is no loss of uncorrected visual acuity, symptoms can be prolonged, especially without prompt steroid therapy. Technical advances that reduced pulse energies appear to decrease the incidence.

摘要

目的

描述与飞秒制瓣准分子原位角膜磨镶术(LASIK)后异常光敏反应相关的主观和客观发现,并确定最佳管理策略。

方法

记录来自3个不同地点的3位外科医生治疗的疑似短暂性术后光敏反应病例的人口统计学数据、激光参数、主观症状、临床发现、治疗方法及治疗反应。对每个地点疑似病例的时间段进行估算以评估发病率。通过一项调查向IntraLase用户征集更多病例。

结果

在3个地点,共报告了33例患者的63只眼,总病例记录估计为5667例(发病率1.1%)。平均年龄为41岁,51.7%的患者为女性。症状在LASIK手术顺利完成后2至6周出现。所有患者均使用醋酸泼尼松龙滴眼液治疗,而1位外科医生还使用了Restasis(0.05%环孢素眼用溶液)。患者在治疗1周内症状有所改善。当光栅和侧切能量参数降低(分别平均降低24%和33%)时,发病率显著降低。在IntraLase用户调查中,另外3位外科医生报告了17例类似发现。

结论

本报告描述了飞秒激光角膜刀进行LASIK手术的一种新并发症,可能与制瓣所用的脉冲能量有关。虽然未矫正视力没有下降,但症状可能会持续很长时间,尤其是在没有及时使用类固醇治疗的情况下。降低脉冲能量的技术进步似乎能降低发病率。

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