Shimoda Takuya, Koizumi Wasaburou, Tanabe Satoshi, Higuchi Katuhiko, Sasaki Tohru, Nakayama Norisuke, Azuma Mizutomo, Saigenji Katsunori, Katou Tomoya, Ogino Mieko
Department of Internal Medicine, Kitasato University East Hospital, Sagamihara, Kanagawa 228-8555, Japan.
Jpn J Clin Oncol. 2006 Feb;36(2):109-12. doi: 10.1093/jjco/hyi241.
We describe a case of small-cell carcinoma of the esophagus associated with a paraneoplastic neurological syndrome. Sensorimotor neuropathy had developed 3 years earlier, and neurological symptoms had slowly worsened. Small-cell carcinoma of the esophagus was incidentally diagnosed while investigating the cause of the neurological symptoms. A paraneoplastic neurological syndrome was diagnosed on the basis of cancer and exclusion of other known causes of neurological symptoms. The patient was given combination chemoradiotherapy. There was a complete response to three courses of chemoradiotherapy, with no evidence of disease recurrence 6 years after the diagnosis. There was no progression of paraneoplastic neurological symptoms after the complete response.
