通过调整抗真菌预防措施和感染控制措施，解决了克柔念珠菌在血液学患者中的传播问题。
Candida krusei transmission among hematology patients resolved by adapted antifungal prophylaxis and infection control measures.
作者信息
Vos Margreet C, Endtz Hubert P, Horst-Kreft Deborah, Doorduijn Jeanette, Lugtenburg Elly, Verbrugh Henri A, Löwenberg Bob, de Marie Siem, van Pelt Cindy, van Belkum Alex
机构信息
Department of Medical Microbiology & Infectious Diseases, Erasmus Medical Center, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
出版信息
J Clin Microbiol. 2006 Mar;44(3):1111-4. doi: 10.1128/JCM.44.3.1111-1114.2006.
Abstract
A sudden increase in neutropenic hematology patients with Candida krusei colonization and bacteremia prompted a longitudinal epidemiological investigation. We identified 39 patients; 13 developed candidemia, and three died; 25 patients carried the same genotype. We intervened by changing antifungal prophylaxis and implementing strict infection control measures. The incidence dropped immediately.
摘要
克鲁斯念珠菌定植和菌血症导致的中性粒细胞减少血液学患者突然增加，促使我们开展了一项纵向流行病学调查。我们确定了39名患者；其中13人发生念珠菌血症，3人死亡；25名患者携带相同基因型。我们通过改变抗真菌预防措施和实施严格的感染控制措施进行干预。发病率立即下降。
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