Beeson Pélagie M, Magloire Joël G, Robey Randall R
Department of Speech, Language, and Hearing Sciences, The University of Arizona, Tucson, AZ 85721-0071, USA.
Behav Neurol. 2005;16(4):191-202. doi: 10.1155/2005/413962.
The present investigation provides a longitudinal study of an individual (RB) with acquired alexia following left posterior cerebral artery stroke. At initial testing, RB exhibited acquired alexia characterized by letter-by-letter (LBL) reading, mild anomic aphasia, and acquired agraphia. Repeated measures of reading accuracy and rate were collected for single words and text over the course of one year, along with probes of naming and spelling abilities. Improvements associated with natural recovery (i.e., without treatment) were documented up to the fourth month post onset, when text reading appeared to be relatively stable. Multiple oral reading (MOR) treatment was initiated at 22 weeks post-stroke, and additional improvements in reading rate and accuracy for text were documented that were greater than those expected on the basis of spontaneous recovery alone. Over the course of one year, reading reaction times for single words improved, and the word-length effect that is the hallmark of LBL reading diminished. RB's response to treatment supports the therapeutic value of MOR treatment to in LBL readers. His residual impairment of reading and spelling one-year post stroke raised the question as to whether further progress was impeded by degraded orthographic knowledge.
本研究对一名因左后大脑动脉中风而获得性失读症的个体（RB）进行了纵向研究。在初始测试中，RB表现出以逐字母（LBL）阅读、轻度命名性失语和获得性失写症为特征的获得性失读症。在一年的时间里，收集了对单个单词和文本的阅读准确性和速度的重复测量数据，以及命名和拼写能力的测试数据。记录了与自然恢复（即未经治疗）相关的改善情况，直至发病后第四个月，此时文本阅读似乎相对稳定。中风后22周开始进行多次口语阅读（MOR）治疗，记录到文本阅读速度和准确性的进一步改善，且大于仅基于自发恢复所预期的改善。在一年的时间里，单个单词的阅读反应时间有所改善，LBL阅读的标志性词长效应减弱。RB对治疗的反应支持了MOR治疗对LBL阅读者的治疗价值。他中风一年后阅读和拼写的残余损伤提出了一个问题，即进一步的进展是否受到拼写知识退化的阻碍。
