Kumar Atul, Chhabra Manpreet S, Prakash Gunjan, Kulkarni Amol D
Centre for Ophthalmic Sciences, All India Institute of Medical Science, New Delhi, India.
Can J Ophthalmol. 2005 Dec;40(6):725-8. doi: 10.1016/S0008-4182(05)80089-4.
We document a previously unreported association of Vogt-Koyanagi-Harada (VKH) syndrome with intracranial meningioma. A female patient with diminished vision, exudative retinal detachment, and headache was diagnosed with VKH syndrome, more precisely a Harada form of disease with intracranial meningioma, on the basis of exudative retinal detachment, typical fundus fluorescein findings, and magnetic resonance imaging. With intravenous steroid therapy, visual acuity improved and the detachment settled within a week. At 3 months, the detachment recurred but improved after retreatment. At 1 year, the tumour was unchanged in size.
VKH syndrome may be associated with intracranial meningioma that may affect the patient's overall morbidity or mortality.
我们记录了葡萄膜炎-白癜风-脱发-耳鸣综合征（VKH综合征）与颅内脑膜瘤之间一种此前未被报道的关联。一名视力减退、伴有渗出性视网膜脱离和头痛的女性患者，基于渗出性视网膜脱离、典型的眼底荧光素检查结果以及磁共振成像，被诊断为VKH综合征，更确切地说是伴有颅内脑膜瘤的原田型疾病。通过静脉注射类固醇治疗，视力在一周内得到改善，视网膜脱离也得到缓解。3个月时，视网膜脱离复发，但再次治疗后有所改善。1年时，肿瘤大小未变。
VKH综合征可能与颅内脑膜瘤相关，这可能会影响患者的总体发病率或死亡率。
