Montero Javier A, Sanchis M Eugenia, Fernandez-Munoz Marta
VISSUM, Instituto Oftalmológico de Alicante, Retina Unit, Alicante, Spain.
J Neuroophthalmol. 2007 Mar;27(1):36-40. doi: 10.1097/WNO.0b013e3180325d84.
A 34-year-old woman in whom multiple sclerosis (MS) had been diagnosed 2 years earlier developed progressive bilateral visual loss associated with peripapillary exudative retinal detachment and other features of Vogt-Koyanagi-Harada (VKH) syndrome. She was treated with corticosteroid pulses and interferon beta-1A with visual acuity improvement and resolution of the retinal detachment. This is the first reported case of VKH syndrome in a patient with MS. The combination of VKH syndrome and MS suggests a common autoimmune pathogenesis.
一名34岁女性，两年前被诊断为多发性硬化症（MS），现出现进行性双侧视力丧失，伴有视乳头周围渗出性视网膜脱离及Vogt-小柳-原田（VKH）综合征的其他特征。她接受了糖皮质激素冲击治疗和干扰素β-1A治疗，视力得到改善，视网膜脱离也得以消退。这是首例报道的MS患者并发VKH综合征的病例。VKH综合征与MS并存提示存在共同的自身免疫发病机制。
