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尼泊尔西部儿童中新出现的机会性原生动物和肠道致病性原生动物感染情况

Emerging opportunistic protozoa and intestinal pathogenic protozoal infestation profile in children of western Nepal.

作者信息

Easow Joshy Maducolil, Mukhopadhyay Chiranjoy, Wilson Godwin, Guha Simantee, Jalan Basavaraj Yogitha, Shivananda Padavagadu Ganapati

机构信息

Department of Microbiology, Manipal College of Medical Sciences, Pokhara, Nepal.

出版信息

Nepal Med Coll J. 2005 Dec;7(2):134-7.

PMID:16519082
Abstract

Intestinal parasitic infestation continues to be of public health importance in many tropical and subtropical countries for their high prevalence and effects on the morbidity in the population. This 5-year hospital-based retrospective analysis was aimed to find out the intestinal protozoal parasitic profile in 1790 pre-school and school-going children visiting the hospital with gastrointestinal illness. Giardia lamblia was the most prevalent pathogenic protozoan intestinal parasite (73.4%), followed by Entamoeba histolytica (24.4%). Interestingly, "newer" opportunistic pathogens like Cyclospora cayetanensis (1.0%) and Cryptosporidium sp. (1.0%) were detected from immunocompromised children below 2 years of age as a result of vertical transmission, which is alarming for a country like Nepal at the stage of 'concentrated epidemic' of HIV infection.

摘要

由于肠道寄生虫感染在许多热带和亚热带国家的高流行率及其对人群发病率的影响,其仍然具有公共卫生重要性。这项基于医院的5年回顾性分析旨在了解1790名因胃肠道疾病前来医院就诊的学龄前和学龄儿童的肠道原生动物寄生虫谱。蓝氏贾第鞭毛虫是最常见的致病性原生动物肠道寄生虫(73.4%),其次是溶组织内阿米巴(24.4%)。有趣的是,通过垂直传播在2岁以下免疫功能低下的儿童中检测到了“新型”机会性病原体,如卡耶塔环孢子虫(1.0%)和隐孢子虫属(1.0%),这对于处于艾滋病毒感染“集中流行”阶段的尼泊尔这样的国家来说是令人担忧的。

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