Dib Hassan H, Lu Si Qi, Wen Shao Fang
School of Public Health, Health Policy and Management, Peking University Health Science Center, Beijing, 100083, China.
Parasitol Res. 2008 Jul;103(2):239-51. doi: 10.1007/s00436-008-0968-6. Epub 2008 Apr 22.
This article is a review of the latest information on the prevalence of G. lamblia in South Asia, South East Asia and Far East, characterizing the current endemic situation within these regions. Around 33 published papers from 2002-2007 were collected on G. lamblia. The included countries were Nepal, Bangladesh, India, Cambodia, Vietnam, Malaysia, Philippines, Indonesia, Thailand, Republic of Korea, and China. Only five published papers were discarded because data was extracted before 2002-2007 or they are not included within our regions, emphasizing more on G. lamblia in animals, or performed at extensive molecular level. The prevalence of G. lamblia varied markedly between studies illustrating higher levels in the urban than in the rural areas, more among poor communities, slightly higher in males than in females with age range of 2-5-year-old children, and among university students, old-aged people, HIV-positive patients, and gastric carcinoma patients. Though G. lamblia is not a life-threatening parasite, nevertheless, it is still considered as the most common water-borne diarrhea-causing disease. It is important to understand the etiology, frequency, and consequences of acute diarrhea in children. Routine surveillance such as bi-annual follow-up treatments, treating G. duodenalis cysts and other protozoa oocysts detected in ground water sources, and continuous health education are the most preventive measures.
本文综述了南亚、东南亚和远东地区蓝氏贾第鞭毛虫的流行情况最新信息,描述了这些地区当前的地方病状况。收集了2002年至2007年间发表的约33篇关于蓝氏贾第鞭毛虫的论文。所涵盖的国家有尼泊尔、孟加拉国、印度、柬埔寨、越南、马来西亚、菲律宾、印度尼西亚、泰国、韩国和中国。仅五篇发表的论文被剔除,原因是数据提取时间早于2002年至2007年,或不属于我们所关注的地区,或更多关注动物体内的蓝氏贾第鞭毛虫,或在广泛分子层面开展研究。蓝氏贾第鞭毛虫的流行率在不同研究间差异显著,表明城市地区高于农村地区,贫困社区人群感染率更高,2至5岁儿童、大学生、老年人、艾滋病毒阳性患者及胃癌患者中男性感染率略高于女性。尽管蓝氏贾第鞭毛虫并非致命寄生虫,但它仍被视为最常见的经水传播的致腹泻疾病。了解儿童急性腹泻的病因、发病率及后果很重要。常规监测,如每半年进行随访治疗、处理地下水源中检测到的十二指肠贾第虫囊肿及其他原生动物卵囊,以及持续开展健康教育,是最有效的预防措施。