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意大利冠心病的社会经济不平等:一项基于人群的多层次研究。

Socioeconomic inequalities in coronary heart disease in Italy: a multilevel population-based study.

作者信息

Petrelli Alessio, Gnavi Roberto, Marinacci Chiara, Costa Giuseppe

机构信息

Epidemiology Unit, Piedmont Region, Grugliasco (TO), Italy.

出版信息

Soc Sci Med. 2006 Jul;63(2):446-56. doi: 10.1016/j.socscimed.2006.01.018. Epub 2006 Mar 7.

Abstract

This longitudinal study evaluates the role of individual and contextual socioeconomic determinants in the socioeconomic inequalities in incidence and mortality for coronary events in Turin, Italy, using hierarchical models. All residents aged 35-74 at the start of 1997 were included in the study population. We considered as outcomes all incident cases and deaths that occurred in the study population in the period 1997-2002. The socioeconomic indicators were educational level, job status and median income per census tract. A neighbourhood deprivation index was also used, which combines, in an aggregated measure, a series of poor individual socioeconomic conditions. The analyses were performed using hierarchical Poisson models, with individuals (n = 523,755) considered as level I units and neighbourhoods (n = 23) as level II units. Among men, we observed an inverse gradient in incidence by educational level and an excess risk for persons who were not actively employed. More marked excesses were found for mortality (RR: 1.63; 95% CI: 1.05-2.55, for unemployed persons compared to employed persons). Among women, greater socioeconomic differences were observed for both incidence and mortality; all of the individual indicators contributed to these differences. The differentials in mortality were particularly great for the retired and for housewives (RR: 1.98; 95% CI: 1.40-2.81). Slight excesses in incidence were observed among men for the most deprived areas. The results of this study reveal that job status is the most important individual factor explaining socioeconomic inequalities for coronary events, whereas context seems to play a marginal role.

摘要

这项纵向研究使用分层模型评估了个体和背景社会经济决定因素在意大利都灵冠心病事件发病率和死亡率的社会经济不平等中的作用。研究人群纳入了1997年初年龄在35 - 74岁的所有居民。我们将1997年至2002年期间研究人群中发生的所有发病病例和死亡视为研究结果。社会经济指标包括教育水平、就业状况和每个普查区的收入中位数。还使用了邻里贫困指数,该指数综合衡量了一系列个体社会经济贫困状况。分析采用分层泊松模型,将个体(n = 523,755)视为一级单位,邻里(n = 23)视为二级单位。在男性中,我们观察到发病率随教育水平呈反向梯度,未积极就业者存在额外风险。在死亡率方面发现了更明显的额外风险(与就业者相比,失业者的风险比RR:1.63;95%置信区间CI:1.05 - 2.55)。在女性中,发病率和死亡率都观察到了更大的社会经济差异;所有个体指标都导致了这些差异。退休人员和家庭主妇的死亡率差异尤为显著(RR:1.98;95%置信区间CI:1.40 - 2.81)。在最贫困地区的男性中观察到发病率略有升高。这项研究的结果表明,就业状况是解释冠心病事件社会经济不平等的最重要个体因素,而背景因素似乎作用较小。

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