Peng M C, Chou W J, Chen S S
Department of Neurology and Psychiatry, Kaohsiung Medical College Hospital, Taiwan, Republic of China.
Gaoxiong Yi Xue Ke Xue Za Zhi. 1991 Aug;7(8):404-12.
In recent years there are a considerable increase in alcohol consumption in Taiwan, which may have been accompanied by increased incidence of alcohol-related physical disease. This study was designed for an understanding of neurological problems in chronic alcoholic patients. One hundred and five cases of chronic alcoholics with neurological problems were collected. All had taken more than 100 g alcohol daily for more than 8 years. They were all males, with a mean age of 47.0 +/- 1.3 years, mean daily alcohol consumption of 185.1 +/- 9.0 g (mean +/- S.E.). These chronic alcoholic patients showed various neurological problems. Patients showing typical clinical features of alcoholic neurological disease are now rather rare. Most of the patients had manifestations of more than one problems: polyneuropathy (74.3%), alcoholic tremor (37.1%), hallucinosis (30.5%), myopathy (26.7%), head injury (24.8%), withdrawal seizures (18.1%), Wernicke encephalopathy (15.2%), paranoia (13.3%), and stroke (15.2%). Furthermore, we divided all the patients into 5 categories, they were: encephalopathy, 59 cases (56.2%); stroke, 16 cases (15.2%); cerebellar degeneration, 12 cases (11.4%); neuropathy, 78 case (74.3%); and myopathy, 28 cases (16.7%). The daily alcohol consumption and duration of daily drinking were different significantly (p less than 0.05) among five different syndrome categories.
近年来,台湾地区的酒精消费量显著增加,这可能伴随着酒精相关身体疾病发病率的上升。本研究旨在了解慢性酒精中毒患者的神经问题。收集了105例有神经问题的慢性酒精中毒患者。所有患者每日饮酒量超过100克,饮酒时间超过8年。他们均为男性,平均年龄为47.0±1.3岁,平均每日酒精消费量为185.1±9.0克(平均值±标准误)。这些慢性酒精中毒患者表现出各种神经问题。表现出典型酒精性神经疾病临床特征的患者现在相当罕见。大多数患者有不止一种问题的表现:多发性神经病(74.3%)、酒精性震颤(37.1%)、幻觉症(30.5%)、肌病(26.7%)、头部损伤(24.8%)、戒断性癫痫发作(18.1%)、韦尼克脑病(15.2%)、偏执狂(13.3%)和中风(15.2%)。此外,我们将所有患者分为5类,分别是:脑病,59例(56.2%);中风,16例(15.2%);小脑变性,12例(11.4%);神经病,78例(74.3%);和肌病,28例(16.7%)。在五种不同综合征类别中,每日酒精消费量和每日饮酒持续时间存在显著差异(p小于0.05)。