Kirby Roger, Offen Nigel
Department of Urology, St George's Hospital, London, UK.
Anticancer Drugs. 2006 Mar;17(3):245-50. doi: 10.1097/00001813-200603000-00002.
A 60-year-old man presented to his general practitioner with prostatic symptoms and high blood pressure. Based upon a prostate-specific antigen level of 44 ng/ml and further investigations (digital rectal examination, transrectal ultrasound-guided needle biopsy, and magnetic resonance imaging, ultrasound and bone scans), the patient was diagnosed with locally advanced (cT3, N0, M0) prostate cancer. Here, the urologist and the patient describe treatment from their respective viewpoints. Following discussion of the advantages and disadvantages of the various therapeutic options, radiotherapy plus hormonal therapy (bicalutamide 150 mg) was chosen as the approach that best suited the patient's lifestyle. In this review, the patient and the urologist consider the impact of the chosen treatment in terms of efficacy, tolerability and quality of life.
一名60岁男性因前列腺症状和高血压就诊于他的全科医生。基于前列腺特异性抗原水平为44 ng/ml以及进一步检查（直肠指检、经直肠超声引导下穿刺活检、磁共振成像、超声和骨扫描），该患者被诊断为局部晚期（cT3、N0、M0）前列腺癌。在此，泌尿科医生和患者从各自角度描述治疗情况。在讨论了各种治疗方案的优缺点后，选择了放疗加激素治疗（比卡鲁胺150 mg）作为最适合患者生活方式的方法。在本综述中，患者和泌尿科医生从疗效、耐受性和生活质量方面考虑了所选治疗的影响。
