Basile C
U.O. Complessa di Nefrologia e Dialisi, Ospedale Generale Regionale Miulli, Acquaviva delle Fonti, BA.
G Ital Nefrol. 2006 Jan-Feb;23(1):22-8.
Intradialytic hypotension (IDH) is one of the most serious complications in renal replacement therapy (RRT). The main cause of IDH is hypovolemia due to an imbalance between the amount of fluid removed and the refilling capacity of the intravascular compartment. IDH occurs when compensatory mechanisms for hypovolemia are overwhelmed by excessive fluid removal. As long as RRT is limited to only a few hours per week, IDH will continue to be a relevant problem. Research has focused mainly on enlarging the compensatory capacity for ultrafiltration-induced hypovolemia. This review critically discusses the technical approaches that have been recently introduced to the therapy with the promise of reducing hypovolemia-induced IDH.
透析中低血压(IDH)是肾脏替代治疗(RRT)中最严重的并发症之一。IDH的主要原因是由于超滤量与血管内容量再充盈能力之间的失衡导致的血容量不足。当血容量不足的代偿机制被过多的超滤所压倒时,就会发生IDH。只要RRT每周仅限制在几个小时,IDH就将仍然是一个相关问题。研究主要集中在扩大对超滤引起的血容量不足的代偿能力上。本综述批判性地讨论了最近引入该治疗方法的技术手段,这些手段有望减少血容量不足引起的IDH。