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The PROactive Study: pioglitazone in the secondary prevention of macrovascular events in patients with type 2 diabetes.

作者信息

Pratley Richard E

出版信息

Curr Diab Rep. 2006 Feb;6(1):45-6. doi: 10.1007/s11892-006-0051-6.

DOI:10.1007/s11892-006-0051-6
PMID:16522280
Abstract
摘要

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The PROactive Study: pioglitazone in the secondary prevention of macrovascular events in patients with type 2 diabetes.PROactive研究:吡格列酮用于2型糖尿病患者大血管事件的二级预防
Curr Diab Rep. 2006 Feb;6(1):45-6. doi: 10.1007/s11892-006-0051-6.
2
The prospective pioglitazone clinical trial in macrovascular events (PROactive): can pioglitazone reduce cardiovascular events in diabetes? Study design and baseline characteristics of 5238 patients.吡格列酮大血管事件前瞻性临床试验(PROactive):吡格列酮能否降低糖尿病患者的心血管事件?5238例患者的研究设计与基线特征
Diabetes Care. 2004 Jul;27(7):1647-53. doi: 10.2337/diacare.27.7.1647.
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[Macrovascular secondary prevention with pioglitazone in diabetics. PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events)].吡格列酮用于糖尿病患者的大血管二级预防。前瞻性吡格列酮大血管事件临床试验(PROactive研究)
Internist (Berl). 2007 Jan;48(1):89-90; discussion 90-1. doi: 10.1007/s00108-006-1777-6.
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PROactive 07: pioglitazone in the treatment of type 2 diabetes: results of the PROactive study.PROactive 07:吡格列酮治疗2型糖尿病:PROactive研究结果
Vasc Health Risk Manag. 2007;3(4):355-70.
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Thiazolidinediones: effects on the development and progression of type 2 diabetes and associated vascular complications.噻唑烷二酮类药物:对2型糖尿病的发生发展及相关血管并发症的影响
Diabetes Metab Res Rev. 2009 Feb;25(2):112-26. doi: 10.1002/dmrr.937.
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[Pioglitazone. Review of its metabolic and systemic effects].[吡格列酮。对其代谢及全身效应的综述]
Rev Clin Esp. 2005 Dec;205(12):610-20. doi: 10.1016/s0014-2565(05)72655-2.
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Redefining the role of thiazolidinediones in the management of type 2 diabetes.重新定义噻唑烷二酮类药物在2型糖尿病管理中的作用。
Vasc Health Risk Manag. 2009;5(1):141-51. doi: 10.2147/vhrm.s4664. Epub 2009 Apr 8.
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How well does the evidence on pioglitazone back up researchers' claims for a reduction in macrovascular events?关于吡格列酮能减少大血管事件的证据在多大程度上支持了研究人员的说法?
BMJ. 2005 Oct 8;331(7520):836-8. doi: 10.1136/bmj.331.7520.836.
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[How does the PROactive Study change therapy of diabetes?].[PROactive研究如何改变糖尿病治疗?]
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PROactive 06: cost-effectiveness of pioglitazone in Type 2 diabetes in the UK.PROactive 06:吡格列酮在英国2型糖尿病治疗中的成本效益
Diabet Med. 2007 Sep;24(9):982-1002. doi: 10.1111/j.1464-5491.2007.02188.x. Epub 2007 Jun 25.

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[Primary prevention of coronary heart disease : Evidence-based drug treatment].冠心病的一级预防:循证药物治疗
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The SGLT-2 Inhibitor Dapagliflozin Has a Therapeutic Effect on Atherosclerosis in Diabetic ApoE Mice.钠-葡萄糖协同转运蛋白2抑制剂达格列净对糖尿病载脂蛋白E基因敲除小鼠的动脉粥样硬化具有治疗作用。
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Peroxisome proliferator-activated receptor-γ agonist pioglitazone ameliorates white matter lesion and cognitive impairment in hypertensive rats.过氧化物酶体增殖物激活受体γ激动剂吡格列酮可改善高血压大鼠的白质病变和认知障碍。
CNS Neurosci Ther. 2015 May;21(5):410-6. doi: 10.1111/cns.12374. Epub 2015 Jan 22.
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DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice.二肽基肽酶-4(CD26)抑制剂阿格列汀抑制糖尿病载脂蛋白 E 缺陷小鼠的动脉粥样硬化。
J Cardiovasc Pharmacol. 2011 Aug;58(2):157-66. doi: 10.1097/FJC.0b013e31821e5626.
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J Steroid Biochem Mol Biol. 2011 Oct;127(1-2):4-8. doi: 10.1016/j.jsbmb.2011.01.005. Epub 2011 Jan 18.