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[Macrovascular secondary prevention with pioglitazone in diabetics. PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events)].

作者信息

Nitschmann S

出版信息

Internist (Berl). 2007 Jan;48(1):89-90; discussion 90-1. doi: 10.1007/s00108-006-1777-6.

DOI:10.1007/s00108-006-1777-6
PMID:17187243
Abstract
摘要

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How well does the evidence on pioglitazone back up researchers' claims for a reduction in macrovascular events?关于吡格列酮能减少大血管事件的证据在多大程度上支持了研究人员的说法？
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Pioglitazone and the risk of cardiovascular events in patients with Type 2 diabetes receiving concomitant treatment with nitrates, renin-angiotensin system blockers, or insulin: results from the PROactive study (PROactive 20).吡格列酮与同时接受硝酸盐、肾素-血管紧张素系统阻滞剂或胰岛素治疗的 2 型糖尿病患者心血管事件风险：来自 PROactive 研究（PROactive 20）的结果。
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Diabetes Care. 2004 Jul;27(7):1647-53. doi: 10.2337/diacare.27.7.1647.
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Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial.2型糖尿病患者大血管事件的二级预防：PROactive研究（吡格列酮大血管事件前瞻性临床试验）：一项随机对照试验
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引用本文的文献

1
Cost-effectiveness of pioglitazone in type 2 diabetes patients with a history of macrovascular disease: a German perspective.吡格列酮治疗有大血管疾病史的 2 型糖尿病患者的成本效益：德国视角。
Cost Eff Resour Alloc. 2009 May 5;7:9. doi: 10.1186/1478-7547-7-9.

本文引用的文献

1
PROactive study.前瞻性随机开放非劣效性对照研究
Lancet. 2006 Jan 7;367(9504):24-5; author reply 26-7. doi: 10.1016/S0140-6736(06)67913-0.
2
The PROactive study: some answers, many questions.PROactive研究：一些答案，诸多问题。
Lancet. 2005 Oct 8;366(9493):1241-2. doi: 10.1016/S0140-6736(05)67504-6.
3
Heart failure prevalence, incidence, and mortality in the elderly with diabetes.老年糖尿病患者的心力衰竭患病率、发病率及死亡率
Diabetes Care. 2004 Mar;27(3):699-703. doi: 10.2337/diacare.27.3.699.
4
Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction.2型糖尿病患者以及有和没有既往心肌梗死的非糖尿病患者的冠心病死亡率。
N Engl J Med. 1998 Jul 23;339(4):229-34. doi: 10.1056/NEJM199807233390404.