在临床实践中识别原发性免疫缺陷。
Recognizing primary immune deficiency in clinical practice.
作者信息
Yarmohammadi Hale, Estrella Lissette, Doucette John, Cunningham-Rundles Charlotte
机构信息
Department of Medicine, Mount Sinai Medical Center, 1425 Madison Ave., New York, NY 10029, USA.
出版信息
Clin Vaccine Immunol. 2006 Mar;13(3):329-32. doi: 10.1128/CVI.13.3.329-332.2006.
Abstract
Primary immunodeficiency results in recurrent infections, organ dysfunction, and autoimmunity. We studied 237 patients referred for suspicion of immunodeficiency, using a scoring system based on clinical information. The 113 patients with immunodeficiency had higher scores and more episodes of chronic illnesses and were more likely to have neutropenia, lymphopenia, or splenomegaly.
摘要
原发性免疫缺陷会导致反复感染、器官功能障碍和自身免疫。我们使用基于临床信息的评分系统，对237名因怀疑免疫缺陷而转诊的患者进行了研究。113名免疫缺陷患者得分更高，慢性病发作次数更多，且更有可能出现中性粒细胞减少、淋巴细胞减少或脾肿大。
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5
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本文引用的文献
1
Molecular defects in T- and B-cell primary immunodeficiency diseases.
Nat Rev Immunol. 2005 Nov;5(11):880-92. doi: 10.1038/nri1713.
2
The multiple causes of human SCID.
J Clin Invest. 2004 Nov;114(10):1409-11. doi: 10.1172/JCI23571.
3
Identifying undiagnosed primary immunodeficiency diseases in minority subjects by using computer sorting of diagnosis codes.
J Allergy Clin Immunol. 2004 Apr;113(4):747-55. doi: 10.1016/j.jaci.2004.01.761.
4
Immune deficiency: office evaluation and treatment.
Allergy Asthma Proc. 2003 Nov-Dec;24(6):409-15.
5
The X-linked hyper-IgM syndrome: clinical and immunologic features of 79 patients.
Medicine (Baltimore). 2003 Nov;82(6):373-84. doi: 10.1097/01.md.0000100046.06009.b0.
6
Immunodeficiency disorders.
Hematology Am Soc Hematol Educ Program. 2003:314-30. doi: 10.1182/asheducation-2003.1.314.
7
Donor immune reconstitution after liver-small bowel transplantation for multiple intestinal atresia with immunodeficiency.
Blood. 2004 Feb 1;103(3):1171-4. doi: 10.1182/blood-2003-04-1187. Epub 2003 Oct 2.
8
Primary immunodeficiency diseases: an update.
Clin Exp Immunol. 2003 Apr;132(1):9-15. doi: 10.1046/j.1365-2249.2003.02110.x.
9
24. Clinical and laboratory assessment of immunity.
J Allergy Clin Immunol. 2003 Feb;111(2 Suppl):S702-11. doi: 10.1067/mai.2003.122.
10
Clinical findings leading to the diagnosis of X-linked agammaglobulinemia.
J Pediatr. 2002 Oct;141(4):566-71. doi: 10.1067/mpd.2002.127711.
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