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3
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4
Classification of primary immunodeficiency disorders: one-fits-all does not help anymore.原发性免疫缺陷病的分类:一刀切已不再适用。
Clin Immunol. 2012 Jul;144(1):24-5. doi: 10.1016/j.clim.2012.05.003. Epub 2012 May 11.
5
Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency.原发性免疫缺陷病:国际免疫学联盟原发性免疫缺陷专家委员会分类更新。
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6
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Advances in primary immunodeficiency diseases in Latin America: epidemiology, research, and perspectives.拉丁美洲原发性免疫缺陷病的研究进展:流行病学、研究和展望。
Ann N Y Acad Sci. 2012 Feb;1250:62-72. doi: 10.1111/j.1749-6632.2011.06289.x.
8
Definition of primary immunodeficiency in 2011: a "trialogue" among friends.2011 年原发性免疫缺陷的定义:朋友之间的“三方会谈”。
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巴西圣保罗市对原发性免疫缺陷疾病的医学认知。

Medical awareness concerning primary immunodeficiency diseases in the city of São Paulo, Brazil.

作者信息

Dantas Ellen de Oliveira, Aranda Carolina Sanchez, Nobre Fernanda Aimée, Fahl Kristine, Mazzucchelli Juliana Themudo Lessa, Felix Erika, Friedlander-Del Nero Dora Lisa, Nudelman Victor, Sano Flavio, Condino-Neto Antonio, Damasceno Elaine, Costa-Carvalho Beatriz Tavares

出版信息

Einstein (Sao Paulo). 2013 Dec;11(4):479-85. doi: 10.1590/s1679-45082013000400013.

DOI:10.1590/s1679-45082013000400013
PMID:24488388
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4880386/
Abstract

OBJECTIVE

To evaluate medical knowledge of primary immunodeficiency in the city of São Paulo (SP).

METHODS

A 14-item questionnaire about primary immunodeficiency was applied to physicians who worked at general hospitals. One of the questions presented 25 clinical situations that could be associated or not with primary immunodeficiency, and the percentage of appropriate answers generated a knowledge indicator.

RESULTS

Seven hundred and forty-six participated in the study, among them 215 pediatricians (28.8%), 244 surgeons (32.7%), and 287 clinicians (38.5%). About 70% of the physicians responded that they had learned about primary immunodeficiency in graduate school or in residency training. Treatment of patients that use antibiotics frequently was reported by 75% dos physicians, but only 34.1% had already investigated a patient and 77.8% said they did not know the ten warning signs for primary immunodeficiency. The knowledge indicator obtained showed a mean of 45.72% (±17.87). Only 26.6% if the pediatricians and 6.6% of clinicians and surgeons showed a knowledge indicator of at least 67% (equivalent to an appropriate answer in two thirds of the clinical situations).

CONCLUSION

There is a deficit in medical knowledge of primary immunodeficiency in the city of São Paulo, even among pediatricians, despite having greater contact with the theme over the last few years. The improvement of information on primary immunodeficiency in the medical community is an important step towards the diagnosis and treatment process of these diseases.

摘要

目的

评估圣保罗市(SP)对原发性免疫缺陷的医学知识掌握情况。

方法

向综合医院的医生发放一份关于原发性免疫缺陷的14项问卷。其中一个问题列出了25种可能与原发性免疫缺陷相关或不相关的临床情况,正确答案的百分比生成一个知识指标。

结果

746人参与了该研究,其中215名儿科医生(28.8%)、244名外科医生(32.7%)和287名临床医生(38.5%)。约70%的医生表示他们是在研究生阶段或住院医师培训期间了解到原发性免疫缺陷的。75%的医生报告了频繁使用抗生素的患者的治疗情况,但只有34.1%的医生曾对患者进行过调查,77.8%的医生表示他们不知道原发性免疫缺陷的十大警示信号。获得的知识指标平均为45.72%(±17.87)。只有26.6%的儿科医生以及6.6%的临床医生和外科医生的知识指标至少为67%(相当于在三分之二的临床情况下回答正确)。

结论

圣保罗市对原发性免疫缺陷的医学知识存在欠缺,即使是儿科医生也是如此,尽管在过去几年中他们与该主题有更多接触。改善医学界关于原发性免疫缺陷的信息是这些疾病诊断和治疗过程中的重要一步。