对比增强对使用磁共振成像测量颈动脉管腔和管壁容积的影响。
Effect of contrast enhancement on the measurement of carotid arterial lumen and wall volume using MRI.
作者信息
Phan Binh An P, Chu Baocheng, Kerwin William S, Xu Dongxiang, Yuan Chun, Hatsukami Thomas, Zhao Xue-Qiao
机构信息
Department of Medicine, University of Washington, Seattle, Washington 98103-8771, USA.
出版信息
J Magn Reson Imaging. 2006 Apr;23(4):481-5. doi: 10.1002/jmri.20540.
PURPOSE
To investigate whether gadolinium (Gd)-based contrast enhancement (CE) affects high-resolution magnetic resonance imaging (MRI) measurements of carotid arterial wall volume.
MATERIALS AND METHODS
The common carotid artery (CCA), bifurcation, and internal carotid artery (ICA) of 50 consecutive patients were imaged using 1.5T MRI. T1-weighted (T1W) images were obtained before and after Gd administration. Pre- and post-CE measurements were compared among different arterial locations of the CCA, bifurcation, and ICA, and among different atherosclerotic lesion types.
RESULTS
In comparison to pre-CE T1W images, post-CE images showed an increase in the apparent wall volume measurement of 28.2% (108.7 mm3 vs. 84.7 mm3, P < 0.001). The post-CE measurement increases in wall volume for the CCA, bifurcation, and ICA were 26.7%, 29.2%, and 28.0%, respectively.
CONCLUSION
Gd CE causes a significant increase in the apparent volume of the carotid wall throughout multiple carotid artery locations, which may be associated with improved visibility or neovascularization.
目的
研究钆（Gd）增强造影（CE）是否会影响颈动脉壁体积的高分辨率磁共振成像（MRI）测量。
材料与方法
对50例连续患者的颈总动脉（CCA）、分叉处和颈内动脉（ICA）进行1.5T MRI成像。在给予钆之前和之后获取T1加权（T1W）图像。比较CE前后在CCA、分叉处和ICA的不同动脉位置以及不同动脉粥样硬化病变类型的测量结果。
结果
与CE前的T1W图像相比，CE后的图像显示表观壁体积测量增加了28.2%（108.7立方毫米对84.7立方毫米，P < 0.001）。CCA、分叉处和ICA的CE后壁体积测量增加分别为26.7%、29.2%和28.0%。
结论
Gd CE导致多个颈动脉位置的颈动脉壁表观体积显著增加，这可能与能见度提高或新生血管形成有关。
Zotero 插件