羽扇豆烷型萜类化合物的生物活性及药理前景：I. 天然羽扇豆烷衍生物
[Biological activity and pharmacological prospects of lupane terpenoids: I. Natural lupane derivatives].
作者信息
Tolstikova T G, Sorokina I V, Tolstikov G A, Tolstikov A G, Flekhter O B
出版信息
Bioorg Khim. 2006 Jan-Feb;32(1):42-55. doi: 10.1134/s1068162006010031.
PMID:16523720
Abstract
The biological activity of natural and semisynthetic lupane triterpenoids is discussed in a two-part review. The first part is devoted to the pharmacological properties of natural lupane triterpenoids. Betulinic acid has proven to be the most effective antitumor agent among more than fifty natural lupanes.
摘要
一篇分两部分的综述讨论了天然和半合成羽扇豆烷三萜类化合物的生物活性。第一部分专门论述天然羽扇豆烷三萜类化合物的药理特性。在五十多种天然羽扇豆烷中，桦木酸已被证明是最有效的抗肿瘤剂。
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