Padmanabhan Prema, Rao Srinivas K, Jayasree R, Chowdhry Mitalee, Roy J
Medical & Vision Research Foundation, Chennai, Tamil Nadu, India.
J Refract Surg. 2006 Feb;22(2):172-7. doi: 10.3928/1081-597X-20060201-16.
To study the wavefront aberration profile of eyes with three different types of intraocular lenses (IOLs)--the Tecnis Z9000 (modified prolate surface design) (Pfizer, New York, NY), the Acrysof MA60BM (unequal biconvex optic) (Alcon, Ft Worth, Tex), and the Sensar Optiedge AR40e (equibiconvex optic) (AMO, Santa Ana, Calif)--in eyes following cataract surgery.
This study was conducted in two parts. The first part was a randomized open study of 32 eyes of 16 patients who underwent bilateral phacoemulsification with a foldable IOL in the capsular bag. A Tecnis Z9000 IOL was implanted in one eye and an Acrysof MA60BM IOL in the fellow eye. The ALLEGRETTO WAVE Analyzer (Wavelight Laser Technologies AG, Erlangen, Germany) was used to measure ocular aberrations 2 weeks after surgery. A paired t test was used to compare each Zernike term from Z3(-3) to Z6(6) between fellow eyes (pupil diameter = 6 mm). In the second part of the study, the wavefront aberrations of 16 eyes that underwent an identical surgical procedure as in the first part of the study but had a Sensar Optiedge AR40e IOL implanted were studied and compared with eyes with the Tecnis Z9000 and Acrysof MA60BM IOLs.
The mean spherical aberration (Z4(0)) was statistically significantly lower in eyes with a Tecnis Z9000 IOL (Z4(0) = 0.07 +/- 0.12 microm) compared with eyes with an Acrysof MA60BM IOL (Z4(0) = 0.29 +/- 0.20 microm, P < .001) and with eyes with a Sensar Optiedge AR40e IOL (Z4(0) = 0.20 +/- 0.09 microm, P = .002). No statistically significant differences were noted in any of the Zernike terms between eyes with Acrysof MA60BM and Sensar Optiedge AR40e IOLs, or in the root-mean-square (RMS) of total higher order aberrations among the three IOL groups.
The implantation of a Tecnis Z9000 IOL produces a significant reduction in spherical aberration of the eye. No significant differences were noted in the wavefront profile between eyes with Acrysof MA60BM and Sensar Optiedge AR40e IOLs. No significant differences were found in the RMS of total higher order aberrations among the three IOL groups.
研究白内障手术后植入三种不同类型人工晶状体（IOL）的眼睛的波前像差情况，这三种人工晶状体分别是：Tecnis Z9000（改良长椭球面设计）（辉瑞公司，纽约州纽约市）、Acrysof MA60BM（不等双凸光学面）（爱尔康公司，得克萨斯州沃思堡）和Sensar Optiedge AR40e（等双凸光学面）（眼力健公司，加利福尼亚州圣安娜）。
本研究分为两部分。第一部分是一项随机开放研究，纳入16例患者的32只眼睛，这些患者均接受了双侧白内障超声乳化手术，并在囊袋内植入了可折叠人工晶状体。一只眼睛植入Tecnis Z9000人工晶状体，另一只眼睛植入Acrysof MA60BM人工晶状体。术后2周使用ALLEGRETTO WAVE像差分析仪（德国埃尔朗根的Wavelight激光技术公司）测量眼部像差。采用配对t检验比较双眼（瞳孔直径 = 6 mm）从Z3（-3）到Z6（6）的每个泽尼克项。在研究的第二部分，对16只接受了与第一部分相同手术操作但植入了Sensar Optiedge AR40e人工晶状体的眼睛的波前像差进行研究，并与植入Tecnis Z9000和Acrysof MA60BM人工晶状体的眼睛进行比较。
与植入Acrysof MA60BM人工晶状体的眼睛（Z4（0）= 0.29 ± 0.20微米，P <.001）和植入Sensar Optiedge AR40e人工晶状体的眼睛（Z4（0）= 0.20 ± 0.09微米，P =.002）相比，植入Tecnis Z9000人工晶状体的眼睛的平均球差（Z4（0））在统计学上显著更低。在植入Acrysof MA60BM和Sensar Optiedge AR40e人工晶状体的眼睛之间，任何泽尼克项均未发现统计学上的显著差异，在三个IOL组的总高阶像差的均方根（RMS）方面也未发现显著差异。
植入Tecnis Z9000人工晶状体可使眼睛的球差显著降低。植入Acrysof MA60BM和Sensar Optiedge AR40e人工晶状体的眼睛之间的波前像差情况未发现显著差异。三个IOL组的总高阶像差的RMS未发现显著差异。
