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使用两种非球面人工晶状体进行白内障手术后角膜像差的变化。

Change in corneal aberrations after cataract surgery with 2 types of aspherical intraocular lenses.

作者信息

Marcos Susana, Rosales Patricia, Llorente Lourdes, Jiménez-Alfaro Ignacio

机构信息

Instituto de Optica Daza de Valdés, Consejo Superior de Investigaciones Científicas, Madrid, Spain.

出版信息

J Cataract Refract Surg. 2007 Feb;33(2):217-26. doi: 10.1016/j.jcrs.2006.10.021.

Abstract

PURPOSE

To study the effect of cataract surgery through 3.2 mm superior incisions on corneal aberrations with 2 types of monofocal intraocular lenses (IOLs) with an aspherical design.

SETTING

Instituto de Optica, Consejo Superior de Investigaciones Científicas, and Fundación Jiménez Díaz, Madrid, Spain.

METHODS

Corneal topography of 43 eyes was obtained before and after small corneal incision cataract surgery. Twenty-two eyes had implantation of a Tecnis Z9000 silicone IOL (Advanced Medical Optics) and 21 had implantation of an AcrySof IQ SN60WF acrylic IOL (Alcon Research Labs) using the recommended injector for each IOL type. The intended incision size (3.2 mm) was similar in the 2 groups. Corneal aberrations were estimated using custom-developed algorithms (based on ray tracing) for 10.0 mm and 5.0 mm pupils. Comparisons between preoperative and postoperative measurements and across the groups were made for individual Zernike terms and root-mean-square (RMS) wavefront error.

RESULTS

The RMS (excluding tilt and defocus) did not change in the AcrySof IQ group and increased significantly in the Tecnis group with the 10.0 mm and 5.0 mm pupil diameters. Spherical aberration and coma-like terms did not change significantly; however, vertical astigmatism, vertical trefoil, and vertical tetrafoil changed significantly with surgery with the 10.0 mm and 5.0 mm pupil diameters (P<.0005). The induced wave aberration pattern for 3rd- and higher-order aberrations consistently showed a superior lobe, resulting from a combination of positive vertical trefoil (Z(3)(-3)) and negative tetrafoil (Z(4)(4)). The mean vertical astigmatism increased by 2.47 microm +/- 1.49 (SD) and 1.74 +/- 1.44 microm, vertical trefoil increased by 1.81 +/- 1.19 microm and 1.20 +/- 1.34 microm, and tetrafoil increased by -1.10 +/- 0.78 microm and -0.89 +/- 0.68 microm in the Tecnis group and AcrySof IQ group, respectively. There were no significant differences between the corneal aberrations in the 2 postoperative groups, although there was a tendency toward more terms or orders changing statistically significantly in the Tecnis group, which had slightly higher amounts of induced aberrations.

CONCLUSIONS

Cataract surgery with a small superior incision induced consistent and significant changes in several corneal Zernike terms (vertical astigmatism, trefoil, and tetrafoil), resulting in a significantly increased overall corneal RMS wavefront error. These results can be used to improve predictions of optical performance with new IOL designs using computer eye models and identify the potentially different impact of incision strategies on cataract surgery.

摘要

目的

研究通过3.2mm上方切口行白内障手术,使用两种非球面设计的单焦点人工晶状体(IOL)对角膜像差的影响。

机构

西班牙马德里光学研究所、科学研究高级理事会以及希门尼斯·迪亚斯基金会。

方法

对43只眼在小切口白内障手术前后进行角膜地形图检查。22只眼植入Tecnis Z9000硅凝胶IOL(Advanced Medical Optics公司),21只眼植入AcrySof IQ SN60WF丙烯酸酯IOL(Alcon Research Labs公司),每种IOL均使用推荐的注射器。两组的预期切口大小(3.2mm)相似。使用定制开发的算法(基于光线追踪)对10.0mm和5.0mm瞳孔的角膜像差进行评估。对术前和术后测量值以及两组间的单个泽尼克项和均方根(RMS)波前误差进行比较。

结果

AcrySof IQ组的RMS(不包括倾斜和离焦)无变化,Tecnis组在10.0mm和5.0mm瞳孔直径时RMS显著增加。球差和类彗差项无显著变化;然而,垂直散光、垂直三叶像差和垂直四叶像差在手术前后,对于10.0mm和5.0mm瞳孔直径有显著变化(P<0.0005)。三阶及更高阶像差的诱导波像差模式始终显示出一个上叶,这是由正垂直三叶像差(Z(3)(-3))和负四叶像差(Z(4)(4))组合而成。Tecnis组的平均垂直散光增加了2.47μm±1.49(标准差)和1.74±1.44μm,垂直三叶像差增加了1.81±1.19μm和1.20±1.34μm,四叶像差分别增加了-1.10±0.78μm和-0.89±0.68μm。术后两组的角膜像差无显著差异,尽管Tecnis组有更多项或阶数在统计学上有显著变化的趋势,该组诱导像差量略高。

结论

上方小切口白内障手术导致几个角膜泽尼克项(垂直散光、三叶像差和四叶像差)出现一致且显著的变化,导致角膜整体RMS波前误差显著增加。这些结果可用于利用计算机眼模型改进对新型IOL光学性能的预测,并确定切口策略对白内障手术潜在的不同影响。

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