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[肌肉活动对大鼠血液中性粒细胞系统的影响]

[The effect of muscle activity on the blood neutrophil system in rats].

作者信息

Morozov V I, Izotova E V, Priiatkin S A, Tsyplenkov P V

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1991 Jan;77(1):53-61.

PMID:1652497
Abstract

The effect of muscular activity (MA) on the amount of different classes of leukocytes in the blood, concentrations of myeloperoxidase and lysozyme in the blood plasma, and neutrophils and phagocytosis parameters of these cells, were studied in rats. The MA resulted in a decrease of marker proteins (myeloperoxidase and lysozyme) concentration in neutrophils and an increase of their concentrations in the blood plasma. The neutrophil phagocytic activity decreased. The restoration of myeloperoxidase content in neutrophils took place within 12 hrs after MA, phagocytic activity restored by the 3rd day. The mechanisms of change of the neutrophil functional activity under the MA influence are discussed.

摘要

研究了肌肉活动(MA)对大鼠血液中不同类型白细胞数量、血浆中髓过氧化物酶和溶菌酶浓度以及这些细胞的中性粒细胞和吞噬作用参数的影响。肌肉活动导致中性粒细胞中标记蛋白(髓过氧化物酶和溶菌酶)浓度降低,而血浆中这些蛋白的浓度升高。中性粒细胞的吞噬活性降低。肌肉活动后12小时内中性粒细胞中的髓过氧化物酶含量恢复,吞噬活性在第3天恢复。讨论了肌肉活动影响下中性粒细胞功能活性变化的机制。

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