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[阿尔茨海默病行为病理学评定量表(BEHAVE-AD):西班牙语版验证]

[Behavioral pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD): Spanish validation].

作者信息

Boada M, Tárraga L, Modinos G, Diego S, Reisberg B

机构信息

Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona.

出版信息

Neurologia. 2006 Jan-Feb;21(1):19-25.

Abstract

INTRODUCTION

The Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD) is a screening instrument for the evaluation of behavioral disturbances in Alzheimer's patients. Our aim was to validate the BEHAVE-AD test in Spanish, intended for use in routine clinical practice.

METHOD

We assessed the validity of the BEHAVEAD in 79 nursing-home patients with diagnosis criteria of dementia, scoring 4 or higher on the Global Deterioration Scale (GDS) scale, by developing a crossed validated form between the Neuropsychiatric Inventory-Questionnaire (NPI-Q) and BEHAVE-AD tests. Both instruments were rated by an expert clinician. In order to study the concurrent validity of some of the BEHAVE-AD subscales, we compared the Cohen-Mansfield Agitation Inventory (CMAI) and the Hamilton Depression Rating Scale (HDRS) tests.

RESULTS

The Pearson correlation index between the BEHAVE-AD test and the NPI-Q, was significant but moderate (r=0.694). Pearson's correlation between BEHAVEAD's symptoms scale and NPI-Q's severity scale was r=0.698. When comparing BEHAVE-AD's global evaluation scale (caregiver's disturbance) and NPI-Q's distress scale, the correlation index was 0.535.

CONCLUSIONS

The BEHAVE-AD Spanish version offers the possibility to use a screening tool for the detection of neuropsychiatric symptoms in dementia patients, also applicable to nursing home residents, administered by an expert clinician.

摘要

引言

阿尔茨海默病行为病理学评定量表(BEHAVE-AD)是一种用于评估阿尔茨海默病患者行为障碍的筛查工具。我们的目的是验证西班牙语版的BEHAVE-AD测试,以便在常规临床实践中使用。

方法

我们通过开发神经精神科问卷(NPI-Q)和BEHAVE-AD测试之间的交叉验证形式,评估了79名符合痴呆诊断标准、在总体衰退量表(GDS)上得分4分或更高的养老院患者中BEHAVE-AD的有效性。这两种工具均由一名专家临床医生进行评分。为了研究BEHAVE-AD某些子量表的同时效度,我们比较了科恩-曼斯菲尔德激越量表(CMAI)和汉密尔顿抑郁评定量表(HDRS)测试。

结果

BEHAVE-AD测试与NPI-Q之间的皮尔逊相关指数显著但中等(r = 0.694)。BEHAVE-AD症状量表与NPI-Q严重程度量表之间的皮尔逊相关性为r = 0.698。比较BEHAVE-AD的总体评估量表(照顾者困扰)与NPI-Q的痛苦量表时,相关指数为0.535。

结论

西班牙语版的BEHAVE-AD提供了一种筛查工具,可用于检测痴呆患者的神经精神症状,也适用于养老院居民,由专家临床医生进行评估。

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