Helmer Catherine, Pasquier Florence, Dartigues Jean-François
Inserm U.593, Université de Bordeaux II, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France.
Med Sci (Paris). 2006 Mar;22(3):288-96. doi: 10.1051/medsci/2006223288.
Alzheimer's disease and related disorders (dementia) are a major public health problem due to the number of cases in the general population, the projections for the future, and the consequences of these diseases. We can estimate that about 850 000 cases of dementia were present in France in 2005 and this number will increase to 1,200,000 in 2020 and 2,100,000 in 2040 if the incidence and the duration of the disease did not change. The development of prevention is therefore necessary. Four ways of prevention are credible. The most important is the treatment of vascular risk factors and particularly hypertension. Other ways are nutritional factors, stimulating leisure activities and depression.
阿尔茨海默病及相关疾病(痴呆症)是一个重大的公共卫生问题,这是由于普通人群中的病例数量、对未来的预测以及这些疾病所带来的后果。我们可以估计,2005年法国约有85万例痴呆症患者,如果疾病的发病率和病程不变,到2020年这一数字将增至120万,到2040年将增至210万。因此,开展预防工作很有必要。有四种预防方法是可信的。其中最重要的是治疗血管危险因素,尤其是高血压。其他方法包括营养因素、促进休闲活动以及治疗抑郁症。