Pandya Nirav K, Piotrowski Gary A, Pottenger Lawrence, Draganich Louis F
Motion Analysis Laboratory, Section of Orthopaedic Surgery and Rehabilitation Medicine, Department of Surgery, The University of Chicago, Chicago, IL 60637, United States.
Gait Posture. 2007 Jan;25(1):106-11. doi: 10.1016/j.gaitpost.2006.02.001. Epub 2006 Mar 10.
The pain associated with knee osteoarthritis (OA) has been shown to lead to an increased propensity to trip on an obstacle. Pain-relieving intra-articular injections are widely utilized in the treatment of knee OA. This study examined the effects of pain-relieving intra-articular knee injections on the ability to avoid contacting a suddenly appearing obstacle in patients with knee OA. Obstacle avoidance success rates, pain, body mass index, visual acuity, contrast sensitivity, depth perception, and single-leg stance duration were evaluated in nine patients with painful osteoarthritis of the knee and 14 age-matched healthy control subjects. Obstacle avoidance success rates, pain, and single leg stance duration were tested a second time in the patients with knee OA after they received their injections, which contained a fast-acting local anesthetic to provide rapid pain relief. After receiving the pain-relieving knee injections, patients with knee OA had 48% less pain and were 31% more successful in avoiding stepping on the obstacle. However, after receiving the injection, the obstacle avoidance success rates remained 20% less than those of the healthy controls. The results of this study suggest that knee pain-relief can decrease the propensity of people with painful knee OA to trip and fall over an obstacle. However, pain-relief alone did not return the patients with knee OA in this study to a disease-free risk of tripping.
已证实，与膝关节骨关节炎（OA）相关的疼痛会导致绊倒在障碍物上的倾向增加。缓解疼痛的关节内注射广泛用于治疗膝关节OA。本研究考察了缓解疼痛的膝关节关节内注射对膝关节OA患者避免接触突然出现的障碍物能力的影响。对9名膝关节疼痛性骨关节炎患者和14名年龄匹配的健康对照者的避障成功率、疼痛程度、体重指数、视力、对比敏感度、深度知觉和单腿站立持续时间进行了评估。膝关节OA患者在接受含有速效局部麻醉剂以快速缓解疼痛的注射后，再次测试避障成功率、疼痛程度和单腿站立持续时间。接受缓解疼痛的膝关节注射后，膝关节OA患者的疼痛减轻了48%，避障成功率提高了31%。然而，注射后，避障成功率仍比健康对照者低20%。本研究结果表明，缓解膝关节疼痛可降低膝关节疼痛性OA患者绊倒在障碍物上的倾向。然而，在本研究中，仅缓解疼痛并未使膝关节OA患者恢复到无绊倒风险的状态。
